Esophageal Motility Disease Screening in Patient With Suspicion or Diagnosis of IBD
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Manometry finding (peristaltic amplitude values mmHG) compared to normal population findings
研究概览
简要总结
Aims: Prospective evaluation of patients with a suspicion or diagnosis of Inflammatory bowel disease (IBD) to evaluate osophageal motility before and during therapy
Material and methods: The investigators prospectively perform manometry in patients with or with symptoms consistent with IBD. The investigators evaluate esophageal motility with high resolution manometry before, during and after IBD therapy. Clinical data are also collected to find possible correlations. The study do not modify the planned IBD therapy, but observe motility findings.
详细描述
Oesophageal motility is measured with the high resolution manometry in order to detect pathologic peristaltic amplitude values among patient before and after therapy (mesalazine, steroids, biologicals) compared to the standard values detected among the normal population. Diagnosic intervention like oesophagoduodenoscopy, colonoscopy and stenosis ballon dilation are allowed as are part of the IBD therapy and follow up.
No other interventions are administered to participants during this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inflammatory bowel disease
- •Suspicion of inflammatory bowel disease
排除标准
- •Pregnancy
结局指标
主要结局
Manometry finding (peristaltic amplitude values mmHG) compared to normal population findings
时间窗: 1 year
Correlation with gastrointestinal symptoms to manometry findings (peristaltic amplitude values)
时间窗: 1 year
次要结局
- Manometry findings (peristaltic amplitude values, mmHG) during therapy(1 year)
研究者
Francesco Vitali
MD
University Hospital Erlangen