JPRN-UMIN000022235已完成3 期
Third line H. pylori eradication therapy with sitafloxacin, amoxicillin and vonaprazan - Third line H. pylori eradication therapy with sitafloxacin, amoxicillin and vonaprazan
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 114
研究概览
简要总结
Even for gyrA mutation positive H.pylori, eradication rate of 7-day VAS regimen achieved 89.7% of successful eradication, which is obviously higher than 10-day EAS regimen. D91 gyrA mutation-positive H. pylori strains were completely eradicated by 7-day VAS regimen. This finding is important in terms of sufficiently reducing the risk of acquiring double mutations.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1. Patients with allergy for quinolones 2. Patients with allergy for PPIs 3. Patients with severe liver injury and/or severe renal damage 4. Pregnancy or possible pregnancy 5. Patients who were recognized as inappropriate for entry
研究者
相似试验
已完成
2 期
Third-line H. pylori eradication therapy with sitafloxacin-including regimePatients with H. pylori eradication failure after the second-line regimenJPRN-UMIN000001558DIvision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine30
已完成
4 期
Evaluation of third-line eradication for H. pylori infection in JapaThe patients after unseccessful 1st and 2nd line eradicationtreatmentJPRN-UMIN000007632Japan Gast Study Group150
已完成
不适用
Efficacy of triple therapy for Helicobacter pylori infection using amoxicillin and clarithromycin and TAK-438 (vonoprazan) which is a novel potassium-competitive acid blocker to the patients treated unsuccessfully with PPI, amoxicillin and clarithromycin.Chronic gastritisJPRN-UMIN000017891Kagawa Prefectural Central Hospital150
已完成
不适用
Third line H. pylori eradication therapy with sitafloxacin, amoxicillin and vonaprazaHelicobacter pylori infectionJPRN-jRCTs031180413Hirata Kenro75
终止
不适用
Ranitidine bismuth citrate pretreatment in H. pylori eradicatioDiseases of the digestive systemKCT0005871Kyung Hee University Hospital at Gangdong114