Antioxidants Vitamins and Muscle Damage
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Percentage of body fat and muscle mass
研究概览
简要总结
Determine if acute supplementation with antioxidant vitamins (vitamin C and vitamin E) influences the muscle damage and fatigue caused after an acute session of eccentric training.
详细描述
A randomized, single-blind, placebo-control parallel trial will be conducted. In a previous session volunteers will be interviewed to determine if they meet the inclusion criteria.
Participants should avoid ingesting of foods that contain high amounts of antioxidant compounds: more than two juices of fruits, more than four cups of coffee or tea. Juices with high antioxidant content should be avoided. Alcoholic beverages should also be avoided. Participants will be divided in to groups and will performance one resistance exercise sessions. Prior to exercise, one group will intake supplementation VitC (1000 mg) + VitE (235 mg) and the other supplementation with placebo.
The following sequence will be performed in each session: 1) baseline assessment (analysis of the composition body, blood draw and parameters of performance) prior to exercise session ; 2) administration of vitamin or placebo supplementation 2 hours before exercise session ; 3) post-exercise assessments (blood biomarkers and performance parameters) immediately after the session and after 24 hours. DOMS will also be assessed 48 h and 72 h after training. The training session implemented will be designed by a Sport Scientific
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 33 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Physically active
排除标准
- •Supplementation or drugs
结局指标
主要结局
Percentage of body fat and muscle mass
时间窗: Prior to the intervention
Determination of body composition using skinfolds measurements
Jump height in a Counter Movement Jump
时间窗: 24 h after exercise
Jump height (cm) in a counter movement jump measured with Octojump Platform
Concentration of blood lactate
时间窗: 2 hours before exercise
Capillary blood lactate with Lactate Pro 2
Blood malondialdehyde (MDA)
时间窗: 24 hours after exercise
MDA will be analyzed from a blood sample
DOMS
时间窗: 24 hours post exercise
Delayed onset muscle soreness. This outcome will be measure with a 10-point visual analogic scale (0= no pain; 10 = worst possible pain)
Blood creatine quinase (CK)
时间窗: 24 hours after exercise
CK will be analyzed from a blood sample
Jump Height in a squat Jump
时间窗: 2 hours prior to exercise
Jump height (cm) in a squat jump with Octojump Platform measured with Octojump Platform
Jump Height in a Squat Jump
时间窗: Inmediately after exercise
Jump Height (cm) in a Squat Jump measured with Octojump Platform
Jump Height in a Drop Jump
时间窗: 24 hours after exercise
Jump height (cm) measured in different drop jumps with Octojump Platform
Contact time in a Drop Jump
时间窗: Inmediately after exercise
Contact time (s)measured in different drop jumps with Octojump Platform
次要结局
未报告次要终点
研究者
María Martínez Ferrán
PhD student, principal investigator
Universidad Europea de Madrid