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临床试验/NCT05882422
NCT05882422已完成不适用

Evaluation of the Effect of Dietary Phytochemical Index and Antioxidant Capacity on the Outcome of Ongoing Pregnancy in in Vitro Fertilization Treatment

Hacettepe University1 个研究点 分布在 1 个国家目标入组 280 人开始时间: 2021年2月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
280
试验地点
1
主要终点
Ongoing pregnancy

研究概览

简要总结

The aim of this study is to determine the relationship between dietary total antioxidant capacity, phytochemical index, inflammatory index, dietary polyphenol intake and ongoing pregnancy outcome in couples receiving IVF treatment.

In this context, the objectives are:

Determining the relationship between diet's antioxidant capacity, phytochemical index, inflammatory index, and dietary polyphenol intake and ongoing pregnancy outcome, Determining the relationship between total serum antioxidant capacity, serum oxidant capacity and CRP levels and ongoing pregnancy outcome, It is the determination of the relationship between body composition and ongoing pregnancy.

With this study, it is aimed to obtain reliable data on the effects of diet's antioxidant capacity, phytochemical index and dietary polyphenol intake and inflammatory index on reproductive functions. In this way, it is thought that nutritional recommendations that can be given to patients who will undergo IVF treatment before treatment will be developed.

In this study, which is a first in terms of examining many parameters related to diets of women and men, it will be evaluated whether the parameters to be examined are effective in IVF cycles.

The aims, objectives and hypotheses the researchers put forward within the scope of the study have not been studied extensively before. If the planned project is carried out successfully, new nutritional approaches will be paved in in-vitro fertilization treatment, and it will be possible to contribute to reducing the financial burden of the treatment. In addition, an important step will be taken to increase the total fertility rate (number of children per woman) within the scope of the 11th Development Plan (2019-2023). It also conforms to the 3rd Sustainable Development Goals, "healthy and quality life" (UNDP Turkey 2018)

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 51 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Females <41 years
  • Males < 55 years
  • BKI ≤ 32 kg/m2

排除标准

  • Smoking cigarettes
  • Chronic and inflammatory diseases
  • Dietary changes in last 6 months
  • Using antioxidant supplements
  • Females diagnosed with infertility for anatomical reasons, endometriosis, tubal factor, or low ovarian reserve
  • Males diagnosed with azospermia
  • Couples who have had more than two failed cycles

结局指标

主要结局

Ongoing pregnancy

时间窗: 1 year

"Ongoing pregnancy" is a term used in reproductive medicine to describe a pregnancy that has progressed beyond the early stages and is continuing to develop with a viable fetal heartbeat. Ongoing pregnancy is typically confirmed by ultrasound examination after the gestational age of 12 weeks. In assisted reproductive technology (ART) cycles, ongoing pregnancy rate is an important outcome measure used to assess the success of the procedure, as it reflects the number of pregnancies that have the potential to result in live births.

次要结局

  • Clinical pregnancy(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nagihan Kırcali Haznedar

Research Assisstant

Hacettepe University

研究点 (1)

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