NCT02217189已完成2 期
Study of the Effect of Oral Zinc Supplementation on Superoxide Radical Scavengers in Spermatozoa of Patients With Asthenospermia
Babylon University2 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2011年7月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- Oxido-sensitive index level in spermatozoa and seminal plasma.
研究概览
简要总结
Although several studies have considered the relationship between infertility and semen super oxide radical scavengers levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on superoxide radical scavengers activity which are important in fertility of the individual has been reported.
详细描述
The present study was conducted to study the effect of zinc supplementation on the quantitative and qualitative characteristics of semen along with superoxide radical scavengers activity in the seminal plasma of asthenospermic patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 26 Years 至 36 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •the presence of asthenozoospermia in the semen sample.
排除标准
- •the absence of endocrinopathy, varicocele, and female factor infertility. Smokers and alcoholic men were excluded from the study because of their recognized high seminal ROS levels and decreased antioxidant levels.
结局指标
主要结局
Oxido-sensitive index level in spermatozoa and seminal plasma.
时间窗: up to three months.
次要结局
- Volume of semen.(up to three months.)
- Xanthine oxidase activity in spermatozoa and seminal plasma.(up to three months.)
- Catalase like activity in spermatozoa and seminal plasma.(up to three months.)
- Superoxide dismutase activity in spermatozoa and seminal plasma.(up to three months.)
- Progressive sperm motility percentage.(up to three months)
- Total normal sperm count.(up to three months.)
研究者
mahmoud hussein hadwan
Mahmoud Hussein Hadwan
Babylon University
研究点 (2)
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