To evaluate the effect of intralipid supplementation on implantation rate in women with two or more failed in vitro fertilization with elevated natural killer cell levels â?? a pilot randomized controlled trial

All India Institute of Medical Sciences0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•For Subjects -
•1.History of two or more failed IVF/ICSI cycle.
•2.Fresh IVF cycles
•3.BMI â?? 19-30 kg/m2
•4.Normal menstrual cycles
•5.Normal ovarian reserve (AMH > 2ng/ml, FSH <9IU, AFC >8)
•6.Factor of infertility â?? unexplained , tubal secondary to ectopic pregnancy and after clipping if hydrosalpinges
•7.Normal uterine cavity, as assessed by hysteroscopy or 4D ultrasonography
•8.Good quality embryos
•9.Normal Partner Semen Analysis including DNA fragmentation index and Reactive oxygen species analysis
•For Controls -
•1.Volunteer
•2.Regular menstrual cycles
•3.No history of infertility
•4.No hormonal treatment for past three months

•1.Donor oocyte IVF/ICSI
•2.Donor Semen IVF
•3.Poor Endometrium <7mm
•4.Polycystic ovary syndrome
•5.OCP use in past three months
•6.Previous history of hysteroscopic adhesiolysis
•7.Severe Male factor infertility requiring surgical sperm retrieval
•8.Moderate to severe Endometriosis
•9.Abnormal parental karyotype
•10.History of known immunological and medical disorders like SLE, Rheumatoid Arthritis, diabetes, congenital or acquired blood dyscrasias
•11.Clinical or laboratory findings of congenital or acquired thrombophilia
•12.Known history of allergic predisposition to soy products, egg products and lecithin

发起方