The Usefulness of the Combination of Preoperative Assessment of Optic Nerve Sheath Diameter and Heart Rate Variability to Predict Intraoperative Brain Condition in Patients With Supratentorial Tumors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Brain relaxation
研究概览
简要总结
This study aims to determine the relationship between heart rate variability and intraoperative brain relaxation conditions in patients with brain tumors.
详细描述
Patients undergoing brain surgery for treatment of brain tumors will be studied to determine the relationship between heart rate variability and intraoperative brain relaxation conditions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient aged 18 to 75 years
- •ASA(American Society of Anesthesiologists ) I - III
- •Patients undergoing surgery for supratentorial tumors
- •Glasgow coma scale > 10
排除标准
- •Patient aged below 18 and above 75 years.
- •Pregnancy
- •ASA(American Society of Anesthesiologists) IV-V
- •Previous cranial surgery
- •Morbid obesity ( BMI>40)
- •Ocular injury/ Glaucoma
- •Head injury
- •Patient on beta blockers, ACE(angiotensin-converting-enzyme) inhibitors, Clonidine
- •Diabetes mellitus for more than 5 years
结局指标
主要结局
Brain relaxation
时间窗: 2hours
1. Tight Brain-the brain surface is jutting out or expanding beyond the craniotomy margins, brain pulsations are not clearly defined. 2. Brain surface at level of craniotomy margins, Brain pulsations faintly observed 3. Brain surface just below the surface of craniotomy margin. Brain pulsations well seen. 4. Brain surface well below the surface of craniotomy margin, well retracted in to the cranial cavity with good brain pulsations.Brain relaxation score will me measured only once. There is no follow up
次要结局
- Hemodynamic Measurement-Heartrate(2hours)
- Hemodynamic Measurement-Bloodpressure(2hours)