Effects of Resistance Training Program on Physical Performance, Health Parameters and Quality of Life in Elderly (RTCHealth)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- % Fat mass
研究概览
简要总结
Physical exercise is considered an important intervention for promoting well-being and healthy aging. The purpose of the present study was to determine the effects of moderate-to-high intensity resistance training circuit on different parameters of fat mass, functional autonomy, strength and quality of life in elderly. A randomized controlled trial was conducted. A total of 45 subjects, (27 females, 18 males) aged between 65-75 years old from Murcia (Spain) were randomly to experimental group (resistance training circuit for 12-weeks and isocaloric diet program) and control group (no resistance training intervention). Fat mass, functional autonomy, muscular strength, perceived exertion, and quality of life perception were obtained with validated tools. Experimental group decreases significantly their fat mass percentage whilst control group not presented differences. Muscular strength results exhibited significant differences between intervention training protocol. Furthermore, experimental group presented better marks than control group at quality of life questionnaire and functional autonomy scores. The moderate-to-high intensity resistance training circuit showed increase in upper and lower muscular strength as well as functional capacity and significantly decreased total fat mass and that improvements in physical function predict improvements in QoL perception in elderly.
详细描述
Participants and study design Figure 1 depicts a flowchart of this study. A total of 75 subjects were recruited from an elderly social groups and voluntarily participated in the study. After 9 subjects were excluded, 66 were ramdomly allocated to either the experimental group (EG, n= 33) or control group (CG, n= 33) at baseline. Subsequently, 25 subjects in the EG y 20 subjects in the CG completed the 12 weeks´follow-up assessments. The general characteristics of the subjects are given in Table 1. All subjects were originally from Murcia, Spain and were chosen according the following inclusion criteria: age ≥ 65 years, they never attended classes of fitness academies or following PA, and had no experience with ST. Exclusion criteria included any history of neuromuscular, metabolic, hormonal, cardiovascular diseases. Subjects were not taking any medication that could influence hormonal and neuromuscular metabolism. Participants were carefully informed about the possible risks and discomforts that could occur and were asked to complete a health history questionnaire and to sign a consent form. This study was performed in accordance with the standards of 1964 Declaration signed in Helsinki, and the protocol was approved by the Ethical Committee of the Catholic University of Murcia (UCAM), Spain.
Data collection pre and post-training (12 weeks) was performed in two days. On the first visit, between 8:00 and 9:00, biological test and quality of life measures were made. On the second day (24 hours after), the submaximal strength test was applied.
Nutrition and dietetics Isocaloric diets based on Mediterranean food were administrated at participants. Diets were analyzed and designed using Diet source software (Novartis, Barcelona, Spain), and were adapted accordingly to each particular subject. Diets were adjusted to strength exercises, including 1-1.2 g of protein/kg of body weight,36-38 25-30% of fat of total kcal and the remaining kcal was completed with carbohydrates as the main macronutrient, corresponding to 55-60% of total kcal. In general terms, the subjects performed 5 daily intakes. Daily energy intakes were adapted according to activity and frequency taking in account training and resting days.
Measures Fat mass Total body weight and % fat mass was measured after removal of shoes and heavy outer clothing, using a Tanita BC-418 MA (Tanita Corporation, Arlington Heights, IL) to the nearest 0.1 kg. Standing height without shoes was measured using a Seca 202 stadiometer (Seca, Hamburg, Germany) to the nearest 0.1 cm. BMI was calculated as the ratio of weight to squared height.
Functional autonomy The Latin American Group for Maturity (GDLAM) protocol was used to evaluate functional autonomy.15,40-42 It is composed of five tests: walking 10 m (W10m); standing up from a seated position (SSP); standing up from a prone position (SPP); standing up from a chair and moving about the room (SCMA); and putting on and taking off a shirt (PTS). These tests are used in a mathematical formula to calculate the GDLAM index (GI). The equipment used consisted of a 48-cm chair (measured from the seat to the floor), a stopwatch (Casio, Malaysia), two cones, a mat (Olive Fitness, Spain) and a sunny brand metal tape measure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 65 Years 至 75 Years(Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 65 years.
- •Never attended classes of fitness academies or following Physical Activity.
- •No experience in Resistance Training.
排除标准
- •No history of neuromuscular, metabolic, hormonal, cardiovascular diseases.
- •Not taking any medication that could influence hormonal and neuromuscular metabolism.
研究组 & 干预措施
Group 1
Experimental group A supervised progressive moderate-to-high RTC program designed to induce muscular hypertrophy was performed. EG followed a progressive moderate-to-high RTC program for 12-weeks. The training program incorporated resistance exercise of six major regions and consisted of 3 training sessions per week on non-consecutive days (Monday, Wednesday and Friday).
All subjects performed the sets with moderate-intensity (8 to 12 repetitions) in each exercise and 30-60 seconds rest between sets. The load was increased during the 12 weeks from 60% 1-RM to high-intensity 80% 1-RM. The training load was increased when the individual could perform more than the prescribed number of repetitions (12 repetitions) followed the OMNI-RES scale and a hard effort perception level. Rest between sets was 1-2 minutes.
干预措施: Exercise test (Other)
Group 2
Control group The CG not participated in the RTC program.
结局指标
主要结局
% Fat mass
时间窗: Change from Baseline bioelectrical impedance % fat mass at 12 weeks
% fat mass was measured after removal of shoes and heavy outer clothing, using a Tanita BC-418 MA (Tanita Corporation, Arlington Heights, IL) to the nearest 0.1 kg.
body weight in kilograms
时间窗: Change from Baseline body weight (kg) at 12 weeks
was measured after removal of shoes and heavy outer clothing, using a Tanita BC-418 MA (Tanita Corporation, Arlington Heights, IL) to the nearest 0.1 kg.
Muscular strength
时间窗: Change from Baseline Muscular Strength at 12 weeks
The predicted 1-repetition maximum (1-RM) testing protocol followed the procedure previously described by Brzycki. Upper body muscles strength and lower body strength was measured
height in meters
时间窗: Change from Baseline standing height (cm) at 12 weeks
Standing height without shoes was measured using a Seca 202 stadiometer (Seca, Hamburg, Germany) to the nearest 0.1 cm.
Quality of life
时间窗: Change from Baseline Quality of Life perception at 12 weeks
Quality of Life in the elderly (WHOQOL-OLD) is an instrument developed by Power et al., translated and validated for the Spanish language. The WHOQOL-OLD is a 24-item self-report instrument that is divided into six Facets. Is also calculated from the set of 24 items. Answers are based on a 5-point Likert response scale
Body Mass Index (BMI)
时间窗: Change from Baseline Body Mass Index (BMI): (kg/m^2) at 12 weeks
was calculated as the ratio of weight to squared height in kg/m\^2
Functional autonomy
时间窗: Change from Baseline Functional autonomy at 12 weeks
The Latin American Group for Maturity (GDLAM) protocol was used to evaluate functional autonomy. It is composed of five tests: W10m; SSP; SPP; SCMA; PTS. These tests are used in a mathematical formula to calculate the GDLAM index (GI).
次要结局
未报告次要终点
研究者
Pablo Jorge Marcos Pardo
Principal investigator
Universidad Católica San Antonio de Murcia
