Evaluation of the Effect of Acute Sodium Bicarbonate Supplementation on Physical Capacity and Blood Biochemical Marker Concentrations in Highly Trained Female Basketball Players

Krzysztof Durkalec-Michalski1 个研究点分布在 1 个国家目标入组 100 人开始时间: 2026年3月1日最近更新: 2026年7月28日

适应症

试验速览

阶段: 3 期
状态: 招募中
发起方
入组人数: 100
试验地点: 1
主要终点: Changes in anaerobic power during the repeated modified Wingate Anaerobic Test

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This randomized, double-blind, placebo-controlled crossover study aims to evaluate the effect of acute sodium bicarbonate supplementation, compared with placebo, on physical capacity and blood biochemical marker concentrations in highly trained female basketball players.

详细描述

Sodium bicarbonate (SB) is commonly proposed as an ergogenic aid due to its potential to enhance extracellular buffering capacity, thereby supporting acid-base balance and delaying fatigue during repeated high-intensity exercise. This mechanism may be particularly relevant in basketball, where performance depends on repeated short-duration, high-intensity efforts, rapid recovery between actions, and the ability to maintain power output during demanding phases of play. Although the ergogenic effects of SB supplementation have been widely investigated, existing evidence has primarily focused on male participants, and data regarding highly trained female athletes remain limited. This creates an important knowledge gap, especially in team sports such as basketball, where sex-specific physiological responses, training status, and sport-specific demands may influence the effectiveness and tolerability of supplementation strategies. This study will evaluate the effect of a single dose of SB compared with placebo. Participants will receive SB or placebo in a randomized, double-blind, placebo-controlled crossover design. The SB dose will be 0.3 g/kg body mass, administered 90 minutes before the exercise protocol, with intervention visits separated by a washout period. By using a randomized, double-blind, placebo-controlled crossover design, this study will allow for the evaluation of individual responses to acute SB supplementation under controlled laboratory conditions. The findings may help clarify whether acute SB intake is an effective and tolerable strategy for supporting physical capacity and biochemical responses in highly trained female basketball players.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Crossover
主要目的: Treatment
盲法: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围: 16 Years 至 35 Years（Child, Adult）
性别: Female
接受健康志愿者: 是

入选标准

•female sex,
•age 16 to 35 years,
•good general health condition and well-being,
•regular menstrual cycles,
•written informed consent to participate in the study before its commencement,
•at least a high level of training status,
•at least 4 years of training experience in basketball,
•participation in at least 3 basketball-specific training sessions per week,
•participation in at least 1 basketball game per week.

排除标准

•male sex,
•use of hormonal contraceptives,
•current injury or musculoskeletal condition limiting participation in training or competition,
•health-related or medical contraindications, including menstrual disorders, planned pregnancy, or anemia,
•use of supplements within 3 months before the study, except for regular use of protein supplements, carbohydrate supplements, or isotonic drinks,
•failure to meet the study protocol assumptions or unwillingness to follow study procedures.