ACTRN12623001242617招募中Unknown
PROlonged versus Single dose in PEnicillin oral Challenge Testing in adult with reported penicillin allergy: A pilot randomized placebo-cOntrolled tRial - The PROSPECTOR Study
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Diagnosis
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1. Adult patients referred to the outpatient allergy clinic or inpatient allergy service for a penicillin allergy history (i.e. amoxicillin or penicillin unspecified)
- •2. Adult patients with an immune-mediated penicillin allergy history with either delayed phenotype (> 2 hours post dose) or unknown timing
- •3. Tolerated first dose of an oral penicillin challenge
- •4. Being challenged to the implicated penicillin. In setting of unknown penicillin, challenge either to penicillin VK or amoxicillin
- •5. Willing and able to give consent
- •6. Willing and able to undergo telehealth or in clinic review post challenge
排除标准
- •1. Patient age is < 18 years;
- •2. Any other illness that, in the investigator’s judgement, will substantially increase the risk associated with subject’s participation in this study
- •3. Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis to beta-lactam
- •4. Inpatients receiving concurrent beta-lactam antibiotic therapy
研究者
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