Sudden Death in Sub-Saharan Africa: Design and Protocol of The DOUALA-SD Prospective Survey
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 240,000
- 试验地点
- 1
- 主要终点
- Sudden death, either cardiac or non-cardiac origin
研究概览
简要总结
Background The burden of sudden death (SD) in sub-Saharan Africa is unknown. The aim is to assess the incidence, etiology and patient characteristics of SD in a sub-Saharan country. Methods The Douala-SD study is a prospective, multicenter, community-based registry monitoring all cases of SD occurring in index areas of Douala city. Investigators will use the definition of SD as natural death occurring within 24h at the onset of symptoms. Demographic, clinical, electrocardiographic and biological variables (when available) of victims will be recorded. All deaths occurring in residents of health areas of interest will be checked for past medical history, circumstances of death, and autopsy (if possible). Conclusion This maiden Douala-SD study will provide comprehensive, contemporary data on the epidemiology of SD in a sub-Saharan African country and will help in the development of strategies to prevent and manage SD in Africa.
详细描述
Two health areas were excluded for inaccurate data collection, and 2 other were randomly disqualified as investigators previously decided to conduct the survey in ≤ 4 areas. The mode of randomization aimed at includes no more than 1 health area per district. Finally, investigators retained 4 health areas representing 4 out of 6 districts of Douala. Thus, the sampling of 240,384 inhabitants will be monitored prospectively. All administrative staff and community-healthcare committee, the so-called " comité de santé" (COSA) of each health area will be a key component of the research team, helping identify every case of death in the area of concern. Every case of death will be reported by the staff of COSA in a specific questionnaire form. In addition to the deaths noted by members of each COSA, investigators will pay attention with all notices of deaths in local newspapers, radio, interrogation of health area residents, and death certificates from local medical centers.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All witnessed and unwitnessed victims of unexpected natural death
排除标准
- •Victims living in the area of interest for a short time frame (< 12 months)
- •Absence of information helping to determine circumstances of death
结局指标
主要结局
Sudden death, either cardiac or non-cardiac origin
时间窗: one year
次要结局
未报告次要终点
研究者
BONNY Aimé
Chief manager
Cameroon Resuscitation Council