The Effect of Stair Descending and Stair Ascending Exercise on Muscle Strength and Performance: the SmartEscalator Device
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Muscle strength (torque)
研究概览
简要总结
The aim of the present project is to compare the acute and chronic effect of stair descending versus stair ascending exercise on muscle damage and performance in elderly males with chronic heart failure.
详细描述
Study design:
Twelve elderly males with chronic heart failure, New York Heart Association class I-II, will participate in this study. Participants will be allocated into two equally-sized groups: a stair descending group (n = 6) and a stair ascending group (n = 6). At the beginning of the study, the volunteers will perform an acute bout of stair descending or stair ascending exercise on an automatic escalator (4 sets of 3 min each, speed will be set at 45 steps∙min-1). Step height will be 20.5 mm. Before and at day 2 post exercise, physiologic measurements will be performed and blood samples will be collected. Then, participants will carry out six weeks of stair descending or ascending training consisting of three exercise sessions per week (the first two weeks the speed will be set at 45 steps∙min-1, the next two weeks at 50 steps∙min-1 and the last two weeks at 55 steps∙min-1 for both groups). Afterward, they will repeat the acute stair descending or ascending protocol, as carried out at the beginning of the study, and the same physiologic measurements will be performed and blood samples will be collected.
Measurements:
Isometric (at 90 knee flexion), concentric and eccentric peak torque at 60o∙s-1of quadriceps femoris, pain-free range of motion, delayed onset muscle soreness and creatine kinase will be measured.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 70 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •chronic heart failure (New York Heart Association class I-II)
- •subject provides written informed consent
- •personal physician of the participants provides written informed consent
排除标准
- •consumed any nutritional supplement the last 3 months
- •performed intense eccentric exercise the last 6 months
- •non Caucasian
研究组 & 干预措施
Stair descending group
Stair descending exercise. Participants will carry out six weeks of stair descending training consisting of three exercise sessions per week.
干预措施: Exercise (Other)
Stair ascending group
Stair ascending exercise. Participants will carry out six weeks of stair descending training consisting of three exercise sessions per week.
干预措施: Exercise (Other)
结局指标
主要结局
Muscle strength (torque)
时间窗: Change from baseline in muscle strength at day 2 post exercise at the first and sixth week of training
An isokinetic dynamometer (Cybex, Ronkonkoma, NY) will be used for the measurement of isometric, eccentric and concentric knee extensor peak torque at 90° knee flexion. The average of the three best maximal voluntary contractions with their dominant leg will be recorded. In order to ensure that the subjects provide their maximal effort, the measurements will be repeated if the difference between the lower and the higher torque value exceeded 10%. There will be two minutes rest between isometric efforts.
次要结局
- Pain free range of motion (degrees)(Before and at day 2 post exercise at the first and sixth week of training)
- Creatine kinase, CK (activity IU)(Before and at day 2 post exercise at the first and sixth week of training)
- Delayed onset muscle soreness, DOMS (scale 1-10)(Before and at day 2 post exercise at the first and sixth week of training)
研究者
Dr. Anastasios Theodorou
Principal investigator
European University Cyprus