The Effectiveness of Psychoeducation and Problem-solving (Life-steps) on Depression and Treatment Adherence in HIV Infected Adolescents: an Exploratory Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Depressive symptoms were measured with Patient Health Questionnaire (PHQ-9), has sensitivity and specificity of 0.8 and 0.7. The cut-off of nine or more was consistent with a diagnosis of depression
研究概览
简要总结
Aim: To explore the effectiveness of psychoeducation and problem-solving (Life-steps) on depression and adherence in HIV-infected adolescents.
Methods: Forty-two adolescents were randomized into 21 controls and 21 intervention groups. The intervention group was exposed to 5-week sessions of life steps applied by a lay counselor. The PHQ-9 and visual analog scale (VAS) were used to measure the outcomes: depression and adherence. They were applied at baseline, 5-weeks, and 24 weeks post-intervention.
详细描述
General objectives
To explore the effect of psychoeducation and problem solving (LIFE STEPS) technique on medication adherence and depression among mentally ill ALWHIV in Botswana.
Specific Objectives
- To compare the sociodemographic and clinical variables of the ALWHIV: intervention and control group
- To explore the effect of psychoeducation and problem solving (LIFE STEPS) on medication adherence and depression among ALWHIV.
Methodology Study Design: Randomised controlled trial to assess the psychological intervention program.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 12 Years 至 19 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •HIV infected adolescents aged, 12 - 19 years
- •On ART for a minimum of six months.
- •Speak or communicate in Setswana or English.
- •Outpatient
- •Willing to participate
排除标准
- •Psychotic, and intellectually disabled patients
结局指标
主要结局
Depressive symptoms were measured with Patient Health Questionnaire (PHQ-9), has sensitivity and specificity of 0.8 and 0.7. The cut-off of nine or more was consistent with a diagnosis of depression
时间窗: 5 weeks
Change in PHQ-9 score or change in depressive symptoms score
次要结局
- Medication adherence: measured with the Visual Analogue Scale (VAS), a horizontal line, 10cm long, and calibrated by 5 from 0 to 100. Score of <95% is suboptimal adherence based on 30 days pill use. It exhibits medium to large strength (r = 0.5-0.7).(5 weeks)