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临床试验/EUCTR2007-000750-31-GB
EUCTR2007-000750-31-GB进行中(未招募)1 期

The effect of long term low dose erythromycin on cough frequency in chronic unexplained cough: a randomised, double blind, placebo conrolled, parallel group trial - macrolides in chronic cough

niversity Hospitals of Leciester NHS trust0 个研究点目标入组 40 人开始时间: 2008年3月18日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

入选标准

  • Cough lasting greater than 8 weeks which remains unexplained after routine clinical assessment as outlined in the British Thoracic Society Cough guidelines document.
  • Normal spirometry values
  • Normal methocholine challange test
  • Normal sputum eosinophillia
  • No response to a 3 month trial of a high dose PPI
  • No response to a trial of a nasal steriod
  • Normal CT thorax
  • Non smokers with a less than 10 pack year smoking history
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Intolerance to macrolides
  • Breastfeeding
  • Unable to consent

研究者

发起方
niversity Hospitals of Leciester NHS trust

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