COMPARATIVE EVALUATION OF CLINICAL EFFECTIVENESS OF BUFFERED AND NONBUFFERED 4% ARTICAINE (WITH ADRENALINE 1:100000) INFILTRATION FOR PRIMARY MAXILLARY MOLAR EXTRACTIONS : AN EXPERIMENTAL STUDY.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- To evaluate clinical effectiveness of buffered and nonbuffered 4% articaine (with adrenaline
研究概览
简要总结
The effective control of pain during dental procedures is an important prerequisite of paediatric dentistry. Though local anaesthetic injections trigger pain and anxiety in children, they continue to be used in dental treatment for children’s comfort, cooperation and pain-free treatment.
Articaine is considered a unique local anaesthetic agent and buccal infiltration with articaine can be used to anaesthetize dental tissues for various dental procedures.
Adrenaline is important in local anaesthetic as it prolong the anaesthetic effect. Lower pH of local anaesthetic solution is set for increasing shelf life of adrenaline. Buffered local anaesthetic have been reported to improve anaesthetic onset and success. Systematic review in medicine have shown reduced injection pain with buffered anaesthetics.
Buffering has been reported to enhance the depth and duration of the anaesthetic level without causing untoward effects on the haemostatic properties of adrenaline when it is added to the solution.
The buffering of lidocaine has been widely evaluated in field of medicine. Though lidocaine is gold standard in local anaesthesia, studies have reported articaine to be more or equally effective when compared to lidocaine in infiltration anaesthesia.
The purpose of this study is to evaluate effectiveness of buffered articaine for primary maxillary molar extractions and pain on injection in children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 4.00 Year(s) 至 10.00 Year(s)（—）
- 性别
- All
入选标准
- •Children Having at least one primary maxillary molar indicated for extraction under local anaesthetic.
- •Children who exhibited Frankl’s behavior rating grade three or four i.e positive and definitely positive.
排除标准
- •Children with active infection at the site of injection.
- •Children with known history of allergy to any local anaesthetic agent.
- •History of major dental treatment in last 6 months.
结局指标
主要结局
To evaluate clinical effectiveness of buffered and nonbuffered 4% articaine (with adrenaline
时间窗: After infiltration anaesthesia
1:100000) infiltration for primary maxillary molar extractions
时间窗: After infiltration anaesthesia
次要结局
- To compare and evaluate pain on injection of buffered and nonbuffered 4% articaine (with adrenaline 1:100000) infiltration for primary maxillary molar extractions.(During infiltration anaesthesia)