Assessment of Risk Factors for Acquiring Colonization With Candida Auris During an Outbreak in ICU.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 771
- 试验地点
- 1
- 主要终点
- Colonization with Candida auris
研究概览
简要总结
The study is aimed to assess the risk factors for acquiring candida auris skin colonization during an outbreak in an ICU.
详细描述
Candida auris is unique when compared to other pathogenic fungi, as it spreads in the hospital rapidly. Therefore, it can cause healthcare-associated infections and outbreaks, it is resistant to antimicrobials and disinfectants and it is persisting on human skin and in the inanimate environment. There are few works listing factors found associated with candida auris candidemia, including longer CVC days, prior antibiotics, mechanical ventilation and longer ICU stay. Most of the research for candida auris risk factor doesn't differentiate colonization and infection, or, focuses on risk factors leading from colonization to infection. The study is aimed to assess the risk factors for acquiring candida auris skin colonization during an outbreak in an ICU.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •hospitalization in ICU
- •Screened for candida auris
排除标准
- •Age <18 yeas.
- •No candida screen.
研究组 & 干预措施
Colonized
Patient colonized with candida auris
Non colonized
Patient not colonized with candida auris
结局指标
主要结局
Colonization with Candida auris
时间窗: From hospitalization in ICU until 2 weeks following discharge from ICU, a maximum of 90 days.
Positive screening for candida auris, taken by nose/ armpits and groin swabs and either directly seeded on a selective medium or by positive PCR.
次要结局
未报告次要终点
研究者
Dr. Daniel Leshin Carmel
Head of infection control
Barzilai Medical Center
