Examining the feasibility and acceptability of a remotely monitored exercise intervention on clinical, immunological and psychological aspects of health in patients with systemic lupus erythematosus

niversity of Birmingham0 个研究点目标入组 45 人开始时间: 2024年1月10日最近更新: 2024年7月8日

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•1. Age >18 years old
•2. Female patients with SLE (fulfilling classification criteria [1997 ACR, 2012 SLICC or 2019 EULAR/ACR). Note: approximately 90% of people suffering with SLE are female, hence this inclusion criteria
•3. Clinically stable disease activity as assessed by a member of the medical team and deemed eligible for inclusion if they have no A or B scores in the BILAG-2004 index
•4. Both participant and physician feel that they are able to exercise safely (PAR-Q screening)
•5. Consent: demonstrates an understanding of the study and willingness to participate, as evidenced by voluntary written informed consent
•Healthy controls:
•1. Age: >18 years old
•National online survey:
•1. Age: >18 years old
•2. Female patients with SLE (fulfilling classification criteria [1997 ACR, 2012 SLICC or 2019 EULAR/ACR). Note: approximately 90% of people suffering with SLE are female, hence this inclusion criteria
•3. Clinically stable disease activity as assessed by a member of the medical team and deemed eligible for inclusion if they have no A or B scores in the BILAG-2004 index
•4. Both participant and physician feel that they are able to exercise safely (PAR-Q screening)
•5. Consent: demonstrates an understanding of the study and willingness to participate, as evidenced by voluntary written informed consent

•Exclusion criteria for exercise intervention:
•1. Increase in the dosage of current lupus-specific medications (e.g., steroids, anti-malarial medications and/or immunosuppressants) within the last 3 months
•2. Addition of new lupus-specific medications (e.g., steroids, anti-malarial medications and/or immunosuppressants) within the last 3 months
•3. Patients with inactive disease but in whom there is a planned change in medication
•4. Uncontrolled blood pressure
•5. Pregnancy or planning pregnancy
•6. Undertaking over 60 minutes of structured exercise per week
•7. Additional health conditions or medication that might put the participant at risk or interfere with a participant’s capacity to exercise will be at the PI’s discretion, e.g., kidney or heart complications
•8. Not owning a smart device or having no data plan or access to WiFi
•9. Unable to provide full informed consent

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