Clarifying the vascular aspects of dementia

none0 个研究点目标入组 280 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•In order to be eligible to participate in this study, a subject must meet the following criteria:
•Patients who attended the memory clinic of the Leiden University Medical Center/ Bronovo hospital within one year ago
•Diagnosed with probable AD
•Diagnosed as MCI
•Diagnosed as SCI
•Diagnosed as VaD
•Capable of giving informed consent (see appendix)
•Control subjects
•Healthy adults without memory complaints aged between 40-90 years old

•A potential subject who meets any of the following criteria will be excluded from participation in this study:
•- Contra-indication to MRI scanning:
•Claustrophobia
•Pacemakers and defibrillators
•Nerve stimulators
•Intracranial clips
•Intraorbital or intraocular metallic fragments
•Cochlear implants
•Ferromagnetic implants
•Hydrocephaluspump
•Intra-utrine device (not all types)
•Permanent make-up
•Tattoos above the shoulders (not all)
•- Specific contraindications to fMRI
•Seizure within prior year.
•Noncorrectable visual impairment.
•- MMSE < 19 points (measured at moment of screening or at memory clinic with a maximum of 6 months in retrospect) (this cutoff was also used in the Leiden 85-Plus study30)
•- Severe physical restrictions (completely wheelchair dependent)
•- Age above 90

发起方

none