Double-blind, randomized, parallel-group, monocentric, placebo-controlled cross-over clinical trial on the effect of a food supplement based on S-adenosyl methionine and probiotics to promote normal mood by reducing subthreshold depression as a risk factor for major depression

Truffini & Reggè Farmaceutici S.r.l.0 个研究点目标入组 80 人开始时间: 2021年8月4日最近更新: 2024年5月6日

适应症

试验速览

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36411659/ (added 19/04/2024)

•1. Male and female in the age range 18 to 65 years
•2. Subjects who present with altered mood tone
•3. Subjects not eligible for antidepressant drugs
•4. Subjects capable of understanding and complying with the requirements of the protocol

•1. Subjects with major depression remission or who have suffered from major depression in recent years
•2. Individuals who have taken products, drugs or dietary supplements with psychological function activities in the 12 weeks prior to recruitment
•3. Subjects suffering from diseases involving the cardiovascular, hepatic, renal, respiratory, nervous or lymphatic system
•4. Subjects suffering from hypothyroidism
•5. Pregnant women and those who have taken monoamine oxidase inhibitors in the 14 days prior to the recruitment

发起方

Truffini & Reggè Farmaceutici S.r.l.