To explore the efficacy and mechanism of Fuyang Jieyu therapy in treating depression disorder with deficiency syndrome based on acid retention, canine urine metabolic pathway and DNA methylati

First Affiliated Hospital of Guangzhou Medical University0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1.Inclusive criteria for the depression disorder with deficiency syndrome group were as follows:
•(1) Current symptoms met the diagnosis of depression according to DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, 5th revision)
•(2) According to Diagnosis of Traditional Chinese Medicine, deficiency syndrome can be identified from the course of disease, constitution, spirit, voice, pain, distension of chest and abdomen, fever, aversion to cold, tongue, pulse and other aspects
•(3) Not caused by psychoactive substances or organic diseases
•(4) 16 years old = age = 60 years old.
•2.Inclusion criteria for the healthy group were as follows:
•(1) a good health record, no physical illness and psychiatric disorder
•(2) Results have been normal in this examination
•(3) no sleeping disorders and digestive dysfunction
•(4) No history of infection, alcohol intake, taking diuretics, antacids, acidulants and drugs that can affect gastrointestinal absorption or renal acid excretion within the previous week

•Exclusion criteria for the depression disorder with deficiency syndrome group were as follows:
•(1) abuse of alcohol and psychoactive substances
•(2) A previous episode of mania or hypomania that met symptom criteria
•(3) pregnant or lactating female patients
•(4) presence of obvious cardiovascular system, respiratory system, liver, kidney, diabetes and other physical diseases
•(5) patients who took diuretics, antacids, acidulants and drugs that can affect gastrointestinal absorption or renal acid excretion in the previous week
•(6) infection history within the past week
•(7) patients confined to wheelchairs

发起方

First Affiliated Hospital of Guangzhou Medical University