Alterations to Appetite Regulation Indices in Adults With Prediabetes Following Short-Term Aerobic vs. Resistance Exercise Training
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Changes in Appetite Rating
研究概览
简要总结
The purpose of the study is to learn about how type of exercise influences measures of appetite regulation.
详细描述
The primary objective of this study is to understand the relationship between exercise modality and appetite regulation in a population with pre-diabetes. The study includes a screening visit to ensure eligibility of participants, baseline assessments, a resistance exercise intervention, and post intervention measurements. The variables of interest include, but are not limited to, hormonal responses to exercise training pertaining to appetite, food cravings, appetite ratings. activity levels, body composition, and ten repetition-max strength. The aim of this study is to better understand the mechanisms involved in the correlation or causation of any improvements in fitness and appetite regulation in a cohort with pre-diabetes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-50 years of age
- •BMI between 27-40 kg/m²
- •Hemoglobin A1c level between 5.7% and 6.4%
- •Physical Activity (less than 150 min/week moderate-intensity Physical Activity, no more than 1 session/week of resistance exercise)
排除标准
- •Unstable Cardiovascular Disease
- •Uncontrolled hypertension
- •Severe hypertriglyceridemia
- •History of or active liver disease
- •Uncontrolled thyroid disease
- •Active cancer diagnosis
- •Engaged in exercise or diet program
- •History of bariatric surgery
- •GI malabsorptive disorders
- •Significant diet intolerances
- •History of major psychiatric disorder
- •presence of alcohol or substance abuse;
- •medications affecting weight,
- •EI or EE in past 6 months;
- •women currently pregnant, lactating, less than 6 months post-partum, or postmenopausal.
结局指标
主要结局
Changes in Appetite Rating
时间窗: Baseline: Pre-Meal , 30 minutes, 60 minutes, 90 minutes, and 120 minutes post meal / Post-intervention(Week 4) :Pre-Meal, 30 minutes, 60 minutes, 90 minutes ,and 120 minutes post meal
Hunger/Satiety before/after consumption of a meal
Changes in Hormonal Response to Feeding
时间窗: Baseline: Pre-Meal , 30 minutes, 60 minutes, 90 minutes, and 120 minutes post meal / Post-intervention(Week 4) :Pre-Meal, 30 minutes, 60 minutes, 90 minutes ,and 120 minutes post meal
Assessment of Ghrelin levels analyzed in blood samples before/after feeding.
次要结局
- Changes in Maximal Strength(Baseline and Post-intervention(Week 4))
- Changes in Physical Activity Levels(Baseline and Post-intervention(Week 4))
- Change in Ad libitum Energy Intake - In lab(Baseline and Post-intervention(Week 4))
- Changes in Body Composition(Baseline and Post-intervention(Week 4))
- Changes in Ad libitum Energy Intake - Free Living(Baseline and Post-intervention(Week 4))
- Changes in Food-Related Behaviors(Baseline and Post-intervention(Week 4))
研究者
Tanya Halliday
Assistant Professor, PhD, RD
University of Utah