The Geneva Lake Study Update : An Overview of Home Non-Invasive Ventilation 15 Years Later
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 947
- 主要终点
- Diagnosis
研究概览
简要总结
A multicenter cross-sectional observational study was conducted in the counties of Geneva and Vaud (1'271'957 inhabitants in 2016 and 1'288'090 inhabitants in 2017 ) and included all subjects under home NIV followed by the two university hospitals of Geneva and Lausanne (HUG and CHUV), one private regional general hospital (La Tour Hospital), one pulmonary rehabilitation center (Rolle Hospital) and 38 pulmonologists in private practice (for a total of 43, 18 in Geneva and 20 in Vaud). In Switzerland home NIV can be prescribed, initiated and followed by a pulmonologist in private practice without referring to a hospital center. The coordinating institution for this project was the Geneva University Hospital (HUG).
The investigator's goals were to update the prevalence of home NIV, the description of the population involved, the devices used, their settings, compliance, and a large array of technical data to provide a complete photography of home NIV in an area with 30 years of experience in this field. We also aimed to collect data regarding pursuit or interruption of NIV and survival during observation period.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All patients aged over 18 years old undergoing long term home NIV for at least 3 months and living in the Cantons of Geneva or Vaud were eligible for the study.
排除标准
- •The only exclusion criteria was invasive ventilation (tracheostomy).
结局指标
主要结局
Diagnosis
时间窗: 01.06.2016-10.07.2018
Diagnosis leading to NIV. 5 disease categories with identification of the percentage of patients with SRBD, COPD, Overlap syndrome, OHS, NMD, restrictive chest wall and lung disorders. All data were analyzed using descriptive statistics. Qualitative parameters were described as frequencies and percentages and quantitative parameters were described as mean and standard deviation (SD) or as median and interval interquartile (IQR). Comparisons between groups were performed using chi-square tests or Fisher exact tests for qualitative parameters and analysis of variance (one-way ANOVA) or Kruskal-Wallis tests for quantitative parameters, as appropriate.
次要结局
- Leaks(01.06.2016-10.07.2018)
- Survival(01.06.2016-01.05.2021)
- Implementation of NIV(01.06.2016-10.07.2018)
- Follow-up modalities(01.06.2016-10.07.2018)
- Baseline characteristics(01.06.2016-10.07.2018)
- Prevalence of home non invasive ventilation (NIV)(01.06.2016-10.07.2018)
- Ventilators(01.06.2016-10.07.2018)
- Barometric and volumetric ventilation versus adaptive servo-ventilation (ASV)(01.06.2016-10.07.2018)
- Medical follow-up(01.06.2016-10.07.2018)
研究者
Jean-Paul Janssens
Professor Jean-Paul Janssens
University Hospital, Geneva