A Multicenter, Observational Cohort to Study the Characteristics of Individuals Asking for Pre-exposure Prophylaxis (PrEP) and the Incidence of HIV and Other Sexually Transmitted Infections: 'The SwissPrEPared Study'
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- HIV Preexposure Prophylaxis
- Sponsor
- University of Zurich
- Enrollment
- 3000
- Locations
- 41
- Primary Endpoint
- Number of individuals asking for PrEP
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
Nested within the SwissPrEPared Program, the "SwissPrEPared Study" - a large, multicentric, nation-wide cohort study - aims to longitudinally follow individuals asking for PrEP prescription over a period of 3 years.
Detailed Description
The main aims of the study will be: 1. To obtain epidemiological data on individuals asking for PrEP in Switzerland. We are particularly interested in: * Determining the extent of PrEP use in Switzerland; * Assessing and monitoring the occurrence of sexually transmitted infections (STIs) in this particular population. 2. To assess sexual health and sexual well-being in individuals asking for PrEP using a questionnaire specifically designed for the SwissPrEPared program.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Participation in the SwissPrEPared program
- •Aged ≥16 years
- •HIV negative
Exclusion Criteria
- •Individuals unable to follow program procedures (e.g. language barriers, mental or psychiatric disorders)
Outcomes
Primary Outcomes
Number of individuals asking for PrEP
Time Frame: 10 years
Number of individuals asking for PrEP
Proportion of individuals qualifying for PrEP according to current guidelines
Time Frame: 10 years
Proportion of individuals qualifying for PrEP according to current guidelines
PrEP regime used (daily, intermittent, on-demand)
Time Frame: 10 years
PrEP regime used (daily, intermittent, on-demand)
Adherence rates to programme
Time Frame: 10 years
Adherence rates to programme assessed via lost to follow-up and dropouts
Occurrence of side effects
Time Frame: 10 years
Occurrence of side effects
Incidence of HIV
Time Frame: 10 years
Incidence of HIV
Mode of drug supply (pharmacy versus online)
Time Frame: 10 years
Mode of drug supply (pharmacy versus online)
Prevalence of HIV
Time Frame: 10 years
Prevalence of HIV
Prevalence of other STIs (syphilis, hepatitis B, hepatitis C, gonorrhoea, chlamydia, mycoplasma genitalium)
Time Frame: 10 years
Prevalence of other STIs (syphilis, hepatitis B, hepatitis C, gonorrhoea, chlamydia, mycoplasma genitalium)
Adherence rates to PrEP
Time Frame: 10 years
Adherence rates to PrEP measured via self-report questionnaire
Incidence of other STIs (syphilis, hepatitis B, hepatitis C, gonorrhoea, chlamydia, mycoplasma genitalium)
Time Frame: 10 years
Incidence of other STIs (syphilis, hepatitis B, hepatitis C, gonorrhoea, chlamydia, mycoplasma genitalium)