Beneficial Effects of Preference on Behavior
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Cognitive Function measured using the Coma Recovery Scale
研究概览
简要总结
Preferred music improves cognitive function in patients with disorders of consciousness (DOC). However, it is still unknown whether it is a general effect of music (because of its acoustic features) or an autobiographical effect (because of its emotional and meaningful contents).
The aim of the present study was to investigate the effect of sensory modality (auditory versus olfactory) and preference (preferred versus neutral) of the testing context on the performance of four items from the coma recovery scale-revised
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Disorders of consciousness (Traumatic brain injury, stroke or anoxic encephalopathy)
- •Coma diagnosis (Plum and Posner, 1966), vegetative state (Task Force, 1994) or minimally conscious state (Giacino, Ashwal et al. 2002)
- •Lack of autonomic crisis since one week minimum
- •Medical condition considered stable
- •Patients who do not present hearing loss. Peaks I and II of Brainstem Auditory Evoked Potentials (BAEP) will be normal.
排除标准
- •Hearing Problem
- •Uncontrolled Epilepsy
- •Autonomic crises
- •Medical unstable state
- •Pregnant or likely to be (interrogation data) or breastfeeding woman
研究组 & 干预措施
patients behavior
Behavior (motor reaction) to stimuli (sounds and odors)
干预措施: sounds and odors (Behavioral)
healthy volunteers behavior
Behavior (motor reaction) to stimuli (sounds and odors)
干预措施: sounds and odors (Behavioral)
结局指标
主要结局
Cognitive Function measured using the Coma Recovery Scale
时间窗: within the first 30 days
Improvement of the score following sound stimuli and/or preferred stimuli
次要结局
- Reaction time(within the first 30 days)