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临床试验/NCT06292442
NCT06292442已完成不适用

Effects of High-Intensity Interval Training on Muscle Strength, Atrophy and Aerobic Capacity in Stroke Patients.

Riphah International University2 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2023年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
34
试验地点
2
主要终点
Muscle Atrophy

研究概览

简要总结

To determine the effects of High-Intensity Interval Training on muscle strength, atrophy, and aerobic capacity in stroke patients.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
40 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Both males and females were included
  • aged 40-60 years
  • Chronic stroke patients who experienced a first-ever ischemic stroke
  • Stable cardiovascular condition (American Heart Association class B)
  • Physician clearance to participate in a 4-week HIIT program
  • No prior structured exercise in the last 3 months
  • Ability to walk 10 m over ground with or without assistive devices
  • Patients who scored >24/30 on MMSE (Mini-Mental State Examination)

排除标准

  • Patients who were hospitalized for cardiac or pulmonary disease within the past 3 months
  • Patients who had implanted pacemaker or defibrillator
  • Patients having conditions where VO2peak assessment is contraindicated, such as uncontrolled hypertension(>180/100), severe aortic stenosis, acute myocarditis, recent myocardial infarction, or other acute cardiovascular events within the past three months, were excluded from the study
  • Patients with severe lower limb spasticity (Ashworth Scale scores >2 of 4 for knee flexion, knee extension, or ankle dorsiflexion)
  • Pregnant females
  • Previous exposure to fast treadmill walking in the past year

结局指标

主要结局

Muscle Atrophy

时间窗: 4th week

Measuring tape is used to measure the calf circumference to measure the atrophy, muscle size over time.

Muscle strength

时间窗: 4th week

Manual Muscle Testing is a test that is used to assess muscle strength.

6-Minute Walk Test (6MWT)

时间窗: 4th week

6-Minute Walk Test (6MWT) used to measure Functional capacity, aerobic fitness and endurance.

Aerobic Capacity

时间窗: 4th week

Harvard Step Test is used to measure Functional capacity, aerobic fitness and endurance.

次要结局

  • Fastest Gait Speed(4th week)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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