Lack of Acute Tolerance Development to Effects of Nitrous Oxide
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- Psychomotor performance
研究概览
简要总结
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To examine the lack of acute tolerance development to the subjective, cognitive, and psychomotor effects of nitrous oxide in healthy volunteers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 21 Years 至 29 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
10% N2O
Subjects will inhale 10% N2O
干预措施: 10% N2O (Drug)
20% N2O
Subjects will inhale 20% N2O
干预措施: 20% N2O (Drug)
30% N2O
Subjects will inhale 30% N2O
干预措施: 30% N2O (Drug)
40% N2O
Subjects will inhale 40% N2O
干预措施: 40% N2O (Drug)
0% N2O
Subjects will inhale 0% N2O
干预措施: 0% N2O (Drug)
结局指标
主要结局
Psychomotor performance
时间窗: During inhalation
Subjects will undergo psychomotor testing during 120 min inhalation session of each intervention
Cognitive performance
时间窗: During inhalation
Subjects will under cognitive testing during 120 minute inhalation session of each intervention
次要结局
未报告次要终点