NCT05321914已完成不适用
The Impact of the Time of Day on Metabolic Responses to Resistance Exercise in Adults Who Are Obese or Overweight: a Randomised Controlled Trial
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Change in insulin sensitivity
研究概览
简要总结
The aim of the current study is to determine the effect of time of day on the muscle and metabolic responses to resistance exercises in obese or overweight adults. To achieve this aim we have the following objectives:
- Compare the effects of resistance exercise training performed in the morning vs the evening on insulin sensitivity
- Compare the effects of resistance exercise training performed in the morning vs the evening on gains in muscle mass and strength
- Compare the acute glucose responses to resistance exercise performed in the morning vs the evening
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •pass the physical activity readiness questionnaire
- •body mass index (BMI) >27kg/m² and limited to 40 kg/m².
排除标准
- •Prior surgery for weight loss
- •Prior history of heart, lung, cancer, endocrine or liver disease
- •Participating in more than 1 hour structured exercise training per week
结局指标
主要结局
Change in insulin sensitivity
时间窗: Change from baseline to 6 weeks
Insulin sensitivity calculated via the Matsuda Index during an oral glucose tolerance test
次要结局
- Change in vastus lateralis muscle thickness(Change from baseline to 6 weeks)
- Change in whole body lean mass(Change from baseline to 6 weeks)
- Change in whole body fat mass(Change from baseline to 6 weeks)
- Change in one-repetition maximum muscle strength(Change from baseline to 6 weeks)
- Change in knee extensor maximal isometric torque(Change from baseline to 6 weeks)
- Change in grip strength(Change from baseline to 6 weeks)
- Change in mean glucose levels(Change from baseline to 6 weeks)
- Change in glucose variability(Change from baseline to 6 weeks)
研究者
Stuart Gray
Senior Lecturer
University of Glasgow
研究点 (1)
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