Evaluation of clinical effects of two probiotic products, Lactogum & ParsiLact-LA on oral health of patients treated with removable and fixed orthodontic appliances

Esfahan University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2021年11月1日

试验速览

暂无简介。

•Patients planned for removable functional orthodontic appliances or full arch both jaws fixed orthodontic appliance therapy.
•Good general health.
•Good oral health (have a dental history that includes brushing at least once a day).
•Be willing and able to comply with the trial regime.
•To have normal tooth anatomy, oral mucosa and periodontal status.

•Inability to obtain informed consent.
•Presence of allergies, food sensitivities or food intolerance.
•Any congenital syndromes of the head and neck.
•Medical contraindications such as heart conditions or Gastrointestinal disorders.
•Any state or diseases necessitating taking immunosuppressants or antibiotics or any medication chronically prior to the procedures.
•Any special physical or mental needs that would compromise patient cooperation.
•History of surgery within the past year or planned to have a surgery in the next 90 days.
•Severe fever, nausea, vomiting, bloody Diarrhea or severe abdominal pain within the past 1 month.
•Chronic use of probiotics or food supplements of any kind and use of antibiotics, steroids, hormones, oral prophylaxis or anti-microbial mouth wash or tooth paste within 1 month before the start of the study.
•Use of products containing xylitol and fluoride or other anti cariogenic products.
•Poor compliance with oral hygiene regimens; poor periodontal health(presence of calculus and/or periodontal pocket); extensive dental restorations or uncontrolled caries activity.

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