Influence of Ambient Temperature on Resting Energy Expenditure of Metabolically Healthy Men and Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Resting Energy Expenditure
研究概览
简要总结
The aim of this study is to investigate the influence of four different ambient temperatures (18, 22, 28, 38°C) on the resting energy expenditure of healthy adults by respiratory gas analysis. It is assumed that the resting energy expenditure is higher at 18°C and 38°C than at the temperatures in between.
详细描述
In a crossover-design, 32 healthy men and women participate in four interventions. Each intervention includes a measurement of the resting energy expenditure by respiratory gas analysis at a different ambient temperature (18,22, 28 and 38°C). During this time body core- and surface temperature are assessed, as well as body composition via bioelectrical impedance analysis. For each participant the four individual study days take place in a randomized order on consecutive weekdays within a week.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI: 18,5 - 24,9 kg/m2
- •metabolically healthy
排除标准
- •low or high blood pressure
- •dyslipidemia
- •insulin resistance or diabetes mellitus type 1 or type 2
- •gastrointestinal diseases (e.g. food intolerances or allergies)
- •liver, kidney and/or thyroid diseases
- •hepatitis B or C, HIV Infection
- •chronic inflammatory diseases
- •disordered eating
- •psychological diseases
- •alcohol and/or drug abuse
- •use of medication
- •pregnancy or lactating
- •participation in another intervention study
- •women: irregular menstrual cycle
- •more than 6 h of sports per week
研究组 & 干预措施
Cold temperature
18°C
干预措施: Respiratory analysis at cold temperature (Other)
Room temperature
22°C
干预措施: Respiratory analysis at room temperature (Other)
Thermoneutral temperature
28°C
干预措施: Respiratory analysis at thermoneutral temperature (Other)
Hot temperature
38°C
干预措施: Respiratory analysis at hot temperature (Other)
结局指标
主要结局
Resting Energy Expenditure
时间窗: 20 minutes
Volume of inhaled oxygen (VO2) in L/min and exhaled carbon dioxide (VCO2) in L/min
次要结局
- Body core temperature(20 minutes)
- Body surface temperature(20 minutes)
- Body composition(5 minutes (after respiratory analysis))
- Blood pressure(10 minutes (at beginning of study day))
研究者
Prof. Dr. Sarah Egert
Prof. PhD
University of Bonn