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临床试验/CTRI/2025/09/094539
CTRI/2025/09/094539尚未招募2/3 期

Comparative Clinical Evaluation of Vachadi Gana and Haridradi Gana Kala Basti in Dyslipidemia

Dr Kritika Verma1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年9月22日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Reduced Levels of Lipid Profile

研究概览

简要总结

Dyslipidemia, characterized by elevated cholesterol, triglycerides, LDL or reduced HDL, is a major risk factor for atherosclerosis. In Ayurveda, it is correlated with Shonita Abhishyanda, a condition arising from Santarpana Nidana such as heavy diet, sedentary lifestyle and incompatible food (Viruddhara) leading to excessive Kapha and Meda in Rasa-Raktavaha Srotas as mentioned in Charaka Samhita, leading to Medoroga. Being Santarpanajanya Vyadhi it requires Apatarpana chikitsa along with srotoshodhana. Basti therapy is considered Ardha Chikitsa  has Lekhana, Chedana and Apatarpana properties that helps in reducing pathological meda and correcting agni. Hence Vachadi Gana and Haridradi Gana are indicated in Medoj and Kaphaja Vikara (i.e. Dyslipidemia) in Shodhanadi Gana adhyaya of Ashtanga Hridyam. In the present trial 30 patients will be enrolled who are diagnosed with Dyslipidemia fulfilling the inclusion and exclusion criteria and dividing them into two groups of 15 each. Group A will receive Vachadi Gana Kala Basti and Group B will receive Haridradi Gana Kala Basti each with a single sitting of 16 days. Clinical outcomes and biochemical parameters ( Lipid Profile including Total Cholesterol, Triglycerides, LDL and HLD) will be assessed to evaluate the efficacy of two interventions. This study aims to establish effective Ayurvedic Treatment approaches for the management of Dyslipidemia under the topic "Comparative Clinical Evaluation of Vachadi Gana and Haridradi Gana Kala Basti in Dyslipidemia."

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
30.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • Patients willing for trial with consent.
  • Patients who are fit for Basti.

排除标准

  • Patients having serious ailments like Insulin Dependant Diabetes Mellitus or poorly controlled Diabetes Mellitus, Myocardial Infarction, Cardiac failure, Renal insufficiency, Hypothyroidism, Malignancies, gluco-corticosteroids induced dyslipidaemia.
  • Patients with Secondary Dyslipidemia.
  • Patients unfit for Basti.
  • Patients on statins/any other drug.
  • Pregnant females and lactating mothers.

结局指标

主要结局

Reduced Levels of Lipid Profile

时间窗: 3 WEEKS

次要结局

  • Changes in levels of Total Cholesterol, Triglycerides, LDL & HDL(8 WEEKS)

研究者

发起方
Dr Kritika Verma
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Kritika Verma

Himalayiya Ayurvedic Pg Medical College And Hospital

研究点 (1)

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