Variable-length Cognitive Processing Therapy for Combat-Related PTSD
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 130
- 试验地点
- 2
- 主要终点
- Change from baseline in PTSD symptoms as measured by thePosttraumatic Stress Disorder Checklist-5 (PCL-5)
研究概览
简要总结
The primary goal of this study is to improve the overall efficacy of cognitive processing therapy-cognitive-only version (CPT-C) in a sample of 130 active-duty service members through a variable length treatment.
详细描述
The primary goal of this study is to improve the overall efficacy of cognitive processing therapy-cognitive-only version (CPT-C) in a sample of 130 active-duty service members through a variable length treatment. The study seeks to determine if some service members would benefit from a longer or shorter dose of treatment (4-24 sessions), and to identify which individuals are likely to require more, less, or the standard number of treatment sessions to reach good end-state functioning. Predictors of length of therapy and treatment outcome will be examined. Specifically, we will evaluate factors related to internalizing/externalizing traits, cognitive flexibility, inability to inhibit dysfunctional cognitions, and readiness to change as they are related to the number of treatment sessions required to treat patients to the point of good end-state functioning. Additional outcomes including alcohol use, psychosocial functioning, physical health, and sleep also will be evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult male and female combat veterans who deployed in support of combat operations following 9/11
- •Diagnosis of PTSD determined by a Clinician-Administered Posttraumatic Stress Scale (CAPS-5)
- •Speak and read English
排除标准
- •Current suicide or homicide risk meriting crisis intervention.
- •Active psychosis.
- •Moderate to severe brain damage (as determined by the inability to comprehend the baseline screening questionnaires).
- •Local availability of fewer than 5 months
- •Late-phase Med Board status, awaiting percentages
- •Undergoing a chapter
研究组 & 干预措施
CPT-C
Cognitive Processing Therapy-Cognitive Only (CPT-C) conducted twice weekly for 4-24 sessions based on good end state functioning.
干预措施: Cognitive Processing Therapy-Cognitive Only (Behavioral)
结局指标
主要结局
Change from baseline in PTSD symptoms as measured by thePosttraumatic Stress Disorder Checklist-5 (PCL-5)
时间窗: Pretreatment, weekly during treatment, 4 weeks, 12 weeks, and 24 weeks posttreatment
PCL-5 measures symptoms of posttraumatic stress disorder in response to a specific stressor.
Change from baseline in PTSD symptoms as measured by the Clinician Administered PTSD Scale (CAPS-5)
时间窗: Pretreatment, weekly during treatment, 4 weeks, 12 weeks, and 24 weeks posttreatment
is an updated version of the gold standard CAPS designed to assess the criteria for PTSD as defined by the DSM-5
次要结局
- Change from baseline in depressive symptoms as measured by the Patient Health Questionnaire-9(Pretreatment, weekly during treatment, 4 weeks, 12 weeks, and 24 weeks posttreatment)