Influence of Respiratory Training on Functional Capacity in Patients With Leukemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Maximum voluntary ventilation
研究概览
简要总结
Forty male leukemic patients receiving chemotherapy were selected from National Cancer Institute, They were randomly assigned into two groups. Group (A) included 30 patients who were trained by Inspiratory muscle trainer for 4 weeks ;5 sessions/week and Group (B) included 10 patients as a control group.
The following measures were taken before and after the study period : Maximum voluntary ventilation(MVV) , 2 min walk test, FACT-G questionnaire
详细描述
Forty male leukemic patients receiving chemotherapy for at least one cycle and their mean ages 37.1 ± 4.89 years.The patients were selected from National Cancer Institute, Cairo ( inpatient ward). The study lasted from March 2018 to June 2018. Patients were randomly assigned into two groups.Group A (30 patients) who received inspiratory muscles training for 4 successive weeks, 5 sessions/week; and Group B (10 patients) acted as a control group on chemotherapy only. Data obtained from both groups regarding (MVV), 2 min walk test and Quality of life questionnaire (FACT-G) were statistically analyzed and compared
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •male patient with age ranges from 30-50 years
- •All patients were leukemic receiving chemotherapy for at least one cycle as a treatment of malignant tumor
- •All patients were hemodynamically stable
- •All patients were ambulant
排除标准
- •lung cancer
- •History of any pulmonary disease.
- •Metastasis of lungs, ribs, mediastinal structure
- •Pulmonary pathology(e.g acute respiratory distress syndrome or exacerbation of chronic obstructive pulmonary disease)
- •ruptured ear drum or any other condition of the ear
- •High peak airway pressure (barotraumas)
- •patients with marked elevated left ventricular end diastolic volume and pressure
- •patients with worsening heart failure signs and symptoms
研究组 & 干预措施
study group (group A)
Group (A) included 30 leukemic patients receiving chemotherapy in addition to training by inspiratory muscle trainer(IMT) for 4 weeks, 5 sessions /week
干预措施: respiratory training (Other)
control group (B)
Group (B) included 10 leukemic patients receiving chemotherapy only
结局指标
主要结局
Maximum voluntary ventilation
时间窗: change from baseline maximum voluntary ventilation at 4 weeks
It was performed by breathing deeply and rapidly for 10 to 15 seconds using spirometer
2 min walk test
时间窗: change from baseline 2 min walk test at 4 weeks
Each patient was asked to cover as much ground as possible over 2 minutes
FACT-G questionnaire
时间窗: change from baseline FACT-G questionnaire at 4 weeks
27 questions with four domains assessing physical well being,social well being, emotional well being and functional wellbeing
次要结局
未报告次要终点
研究者
Heba Ahmed Ali Abdeen
Assistant professor
Cairo University