Fertility in Patients With Untreated Rectosigmoid Endometriosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 215
- 试验地点
- 1
- 主要终点
- Clinical pregnancy rate
研究概览
简要总结
Several studies investigated the reproductive outcomes after surgical treatment of colorectal endometriosis, mainly segmental colorectal resection. Little information is available on the spontaneous fertility of patients with bowel endometriosis. This study aims to evaluate the fertility of patients affected by rectosigmoid endometriosis who did not undergo previous surgical treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Desire of conception
- •Diagnosis of rectosigmoid endometriosis by transvaginal ultrasonography (TVS) and magnetic resonance imaging enema (MR-e)
排除标准
- •Previous surgery for endometriosis
- •Diagnosis of hydrosalpinx at imaging
- •Previous conception
- •Abnormal semen parameters of male partners
结局指标
主要结局
Clinical pregnancy rate
时间窗: 4-9 weeks after conception
Ultrasonographic evidence of intrauterine gestational sac
Live birth rate
时间窗: 22 weeks after conception
Complete expulsion or extraction from a woman of a product of fertilization after 22 completed weeks of gestational age, which, after such separation, breathes or shows any other evidence of life
次要结局
- Number (%) of patients undergoing vaginal delivery/delivering by cesarean section(22-42 weeks after conception)
- Number (%) of patients conceiving spontaneously/by Assisted Reproductive Technology(Immediately after diagnosis of clinical pregnancy)
研究者
Fabio Barra
Principal Investigator
Ospedale Policlinico San Martino