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临床试验/ISRCTN63226989
ISRCTN63226989已完成不适用

The dopaminergic system in patients with functional dyspepsia analyzed by an alpha-methyl-para-tyrosine (AMPT) challenge test and single photon emission computed tomography (SPECT) imaging before and after treatment with amitriptyline

Academic Medical Center (AMC), Department of Gastroenterology (The Netherlands)0 个研究点目标入组 60 人开始时间: 2006年6月7日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Age 18-65 years
  • 2. Functional dyspepsia (Nepean dyspepsia index [NDI] >25)
  • 3. Take part in the amitriptyline study (ISRCTN76116512)
  • 4. No effect on proton pump inhibitor (PPI), or a constant three-month dosage of PPI
  • 5. No depression (Zung self-rating depression scale <50)
  • 6. No medications which influence the intestine

排除标准

  • 1. Gastroduodenal surgery
  • 2. Reflux-like dyspepsia (Rome II criteria)
  • 3. Use of antidepressants
  • 4. Organic abnormalities
  • 5. Pregnancy
  • 6. Severe cardiac, renal, pulmonary, hepatic or systemic diseases, hyperthyroidism, glaucoma and epilepsy
  • 7. Metal implants

研究者

发起方
Academic Medical Center (AMC), Department of Gastroenterology (The Netherlands)

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