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临床试验/NCT06871189
NCT06871189已完成不适用

Age and Gender on TMJ Sound Frequencies and Mouth-Opening Distances

Atlas University1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2024年12月8日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
300
试验地点
1
主要终点
range of motion

研究概览

简要总结

The temporomandibular joint (TMJ) plays a crucial role in masticatory function, and its proper lubrication is essential for smooth, frictionless movement. Disruptions to the lubricating system, often due to age-related changes or parafunctional activities such as teeth clenching or bruxism, can increase joint friction, leading to vibrations or intra-articular sounds. These sounds have become an essential diagnostic tool for assessing internal derangements of the TMJ. While magnetic resonance imaging (MRI) is considered the gold standard for diagnosing TMJ disorders, its limitations in evaluating intra-articular structures have led to the development of alternative methods, such as Joint Vibration Analysis (JVA). This study explores the relationship between age, gender, and TMJ vibration frequencies using JVA in a cohort of 367 participants. We analyzed four key vibration parameters: Range of Motion (ROM), Total Integral Left (TIL), Total Integral Right (TIR), and frequency distributions in the <300 Hz and >300 Hz segments.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
10 Years 至 30 Years(Child, Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Participants capable of achieving an inter-incisal opening of 30 to 50 mm without restrictions.
  • •Free from symptoms indicative of temporomandibular disorder (TMD).
  • •Possessing fully and/or prosthetically restored dentition.
  • •Demonstrating adequate mouth opening to facilitate the rotation of the condylar process.

排除标准

  • •Individuals using psychotropic or narcotic medications, regardless of medical oversight.
  • •Regular consumption of painkillers or anti-inflammatory agents.
  • •Long-term treatment with cortisone or its derivatives. Individuals who have sustained traumatic injuries to the maxillofacial region.
  • •Participants who have suffered the loss of organs and/or tissue in the maxillofacial area due to medical or traumatic causes.

结局指标

主要结局

range of motion

时间窗: The outcome measure was assessed at baseline.

ROM is measured as the maximum mouth opening (mouth opening distance), which is an indicator of joint mobility and dysfunction in TMD patients. Limited or abnormal ROM in the TMJ, reflected by restricted mouth opening, is often associated with pain, dysfunction, and impaired jaw movement, making it a crucial parameter for assessing the severity of TMD.

Total Integral

时间窗: The outcome measure was assessed at baseline

hese parameters assess the intensity and frequency of the joint's movement on each side (left and right). TIL and TIR represent the overall activity and functional performance of the TMJ during movement, with abnormal values potentially indicating dysfunction or asymmetry between the left and right sides. These parameters are critical for evaluating the joint's response to treatment and the presence of any abnormalities in movement or pressure distribution across the TMJ.

Frequency Components

时间窗: The outcome measure was assessed at baseline

The frequency parameters assess the overall movement and condition of the temporomandibular joint (TMJ) by measuring pressure wave activity across different frequency ranges. Integral \> 300 Hz (d1/d2) reflects higher frequency components primarily influenced by joint surface roughness and degenerative changes. Integral \< 300 Hz (c1/c2) represents lower frequency components associated with disc movements, which can be affected by disc displacement, hypermobility, or joint laxity. The Ratio (e1/e2) indicates the ratio of high to low frequencies, providing insight into joint surface condition and overall TMJ health. These parameters are crucial for evaluating the function and possible degeneration of the TMJ.

次要结局

未报告次要终点

研究者

发起方
Atlas University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Serdar Gozler

Dr.

Atlas University

研究点 (1)

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