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临床试验/NL-OMON45709
NL-OMON45709已完成不适用

Pilot study: A comparison of the extent of haemolysis induced by conventional versus miniaturised extracorporeal circulation during coronary artery bypass grafting surgery, and the influence on the release of damage associated molecular patterns (DAMPs), leukocyte activation and neutrophil extracellular trap (NET) formation.<br> - Extent and effect of haemolysis induced by extracorporeal circulation

Amphia Ziekenhuis0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 64(—)

入选标准

  • Elective CABG operation with extracorporeal circulation

排除标准

  • o Kidney insufficiency: creatinine >150 µmol/L
  • o Liver insufficiency: ASAT >80 U/L
  • o Left ventricular function (LVF): <30% Ejection fraction (EF)
  • o Body surface area (BSA): <1.6; *2.1 m²
  • o Carotid artery stenosis
  • o Pre-operative Haemoglobin: <7,5; *10 mmol/L
  • o Pre-operative red blood cell transfusion: <14 days before CABG procedure
  • o Splenectomy (influences the IgM levels used to determine the amount of haemodilution)

研究者

发起方
Amphia Ziekenhuis

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