Comparison of vaginal and sub-lingual misoprestol for induction of therapeutic abortion at 12- 20 weeks gestational age 2012-13

Tehran University of Medical Sciences0 个研究点目标入组 480 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•Inclusion criteria :
•All pregnant women with gestational age between 12 and 20 weeks who have medical indications for pregnancy termination 20-40 years old including fetal indications like structural or chromosomal fetal abnormalities, PROM, intrauterine fetal death or maternal indication such as pregnant women with hemoglobin less than 10 mg.

•pregnant women with any type of allergic reaction to misoprestol,
•pregnant women high risk for rupture of uterine,
•history of classic uterine incision or T-shaped incision,
•women with a history of extensive surgery on the fundus of the uterus, pregnant women with IUD,
•women with certain medical conditions such as severe anemia, clotting disorders or taking anticoagulant medication, active liver disease, glaucoma, uncontrolled seizure disorders, adrenal disease or disorder that requires treatment with glucocorticoids such as tracheobronchial asthma,
•Smoking more than 20 cigarettes per day,
•gynecologic abnormalities confirmed by ultrasound, mitral stenosis,
•sickle cell anemia,
•diastolic blood pressure more than 90 mm Hg, systolic pressure less than 90 mmHg,
•history of thromboembolism and liver disease, hemolytic disorders and a history of two cesareans.

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