Effect of Test Chewing Gums on Oral Malodour and Oral Pathogens

ITC Limited0 个研究点目标入组 78 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1. Males and females, more than or equal to 18 years to less than or equal to 50 years of age
•2. Halimeter reading of T-VSC (total volatile sulphur compounds) of 200 ppb (parts per billion) or more
•3. Salivary levels of S. mutans more than 10,000 CFU/mL
•4. Subjects with non-compromised oral health â?? Subjects should not have untreated caries lesions, clinical signs of gingivitis or periodontal disease, orthodontic patients, oral carcinoma, etc.
•5. Subjects not undergoing antibiotic or antimicrobial therapy
•6. Subjects willing to use standard toothpaste and toothbrush provided to them, throughout the study
•7. Subjects willing to use a tongue cleaner provided to them, throughout the study
•8. Females of child-bearing potential and males should be willing to use adequate methods of contraception
•9. Must be willing and able to give informed consent and comply with the study procedures.

•1. Subjects using fixed orthodontic appliances
•2. Subjects on drugs for xerostomia, e.g. pilocarpine or cevimeline
•3. Subjects who are allergic to any of the ingredients of the study product
•4. Subjects who have undergone long term antibiotic therapy (for 30 days or more in the past three months)
•5. Subjects who are smokers or current users of narcotics
•6. Subjects using commercial mouthwash, antibacterial tooth paste and dental floss
•7. Subjects who are consuming probiotics products in any formats
•8. Pregnant or lactating women
•9. Any additional condition(s) that in the Investigators opinion would warrant exclusion from the study or prevent the subject from completing the study

发起方