Clinical Study of Titrating PEEP of Different Methods on Right Heart Function and Pulmonary Artery Pressure in ARDS Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- the function of right heart and pulmonary artery pressure
研究概览
简要总结
To observe the influence of different methods titrating PEEP on right heart function and pulmonary artery pressure in ARDS patients .
详细描述
30 patients who diagnosed as ARDS were included in this study.Then set PEEP with respectively ARDS net 、EIT and Esophageal Pressure in Breathing Machine . Recorded diameter of right and left ventricular TAM TAPSE pulmonary artery pressure.Objective to evaluate the correlation between the level of PEEP in three methods and the right heart function and pulmonary artery pressure in ARDS patients .
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted to ICU diagnosed of modecate to severe ARDS (Berlin criteria)
- •Patients age between 18 years old and 80 years
排除标准
- •Patients with chronic respiratory diseases such as COPD.
- •Ventilated because of oesophageal surgery in the previous 12months.
- •Patients who cannot obtain clear ultrasound images due to thoracic surgery ,massive pleural effusion.
- •Oesophageal bleeding in previous 30 days history of oesophageal varices.
- •Facial trauma and surgery.
结局指标
主要结局
the function of right heart and pulmonary artery pressure
时间窗: 2018.4-2019.3
Systolic Pulmonary Artery Pressure TAPSE or Tricuspid Annular Motion orTricuspid annular plane systolic excursion or right ventricular diameter or right left ventricular diameter ratio in diffrient PEEP
次要结局
未报告次要终点
研究者
Chun Pan
Clinical Professor
Southeast University, China