The Effect of a Tablet-based Aphasia Therapy in the Chronic Phase After Stroke
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Boston Naming Test (BNT)
研究概览
简要总结
Aphasia is one of the most common and disabling disorders following stroke, in many cases resolving in long-term deficits. There is evidence that intensive aphasia therapy is effective for language recovery, even in the chronic phase post-stroke. However, as many patients are left with residual language disorders and intensive aphasia rehabilitation is difficult to achieve, the investigators are exploring tablet-based therapies to further facilitate language recovery in a cost-effective manner.
详细描述
This study will investigate the clinical effects of intensive tablet-based aphasia therapy as an add-on to conventional aphasia therapy (= high intensive) compared to conventional aphasia therapy (either alone, or in combination with recreational tablet use (= low intensive) in patients with aphasia following stroke, as measured by specific linguistic tests, within task improvements, functional communication and quality of life.
Furthermore, the investigators want to learn more about the recovery of specific underlying language processes via event-related potentials (ERPs). At last, the investigators aim to explore whether patients with aphasia are satisfied with a tablet-based aphasia therapy, whether the app is user-friendly and which barriers the participants might have encountered.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed with mild-severe aphasia (token test score between 7 and 49) after a left hemispheric ischemic or hemorrhagic stroke
- •inclusion starting from 6 months post-stroke
- •age 18 - 85 years
- •being right-handed (according to the questionnaire for handedness, Van Strien)
- •mother tongue: Dutch
- •imaging (CT or MRI) prior to inclusion
- •signed informed consent
排除标准
- •history of a previous stroke with persistent (> 24 hours) language symptoms
- •history of other diseases of the central nervous system, psychological disorders and (developmental) speech and/or language disorders
- •serious non-linguistic, cognitive disorders (as documented in the patients' medical history)
- •inability to perform tablet-based tasks (based on a short training session)
- •excessive use of alcohol or drugs
研究组 & 干预措施
aphasia therapy + speech app
3 hours per week of conventional aphasia therapy during 3 weeks + 5 hours per week during 3 weeks independent practice via the speech app
干预措施: speech app (Device)
aphasia therapy + speech app
3 hours per week of conventional aphasia therapy during 3 weeks + 5 hours per week during 3 weeks independent practice via the speech app
干预措施: aphasia therapy (Behavioral)
aphasia therapy + brain games
3 hours per week of conventional aphasia therapy during 3 weeks + 5 hours per week during 3 weeks of recreational tables use (brain games)
干预措施: brain games (Device)
aphasia therapy + brain games
3 hours per week of conventional aphasia therapy during 3 weeks + 5 hours per week during 3 weeks of recreational tables use (brain games)
干预措施: aphasia therapy (Behavioral)
aphasia therapy
3 hours per week of conventional aphasia therapy during 3 weeks
干预措施: aphasia therapy (Behavioral)
结局指标
主要结局
Boston Naming Test (BNT)
时间窗: 4 months
Measure of word retrieval. Patients will have to name line drawings that gradually increase in difficulty
次要结局
- Usability questionnaire(1 day)
- Quality of life (SAQOL-39-Nl)(4 months)
- Spontaneous speech of the Aachen Aphasia Test (AAT)(4 months)