NCT03619538已完成不适用
Interest of the Nefopam and PCA Morphine Combination for Postoperative Analgesia in Patients Undergoing Colon Surgery
Centre Hospitalier Universitaire de Nīmes1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2007年6月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Estimate morphine consumption
研究概览
简要总结
This study analyses interest of iv nefopam in combination with paracetamol after major abdominal surgery because the effect of morphine-sparing is discussed when combined these agents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patient with a score ASA between I and III
- •Patient scheduled for elective major abdominal surgery (by laparotomy) for cancer or diverticulosis
- •Patient that signed the consent form
排除标准
- •- Patient treated in emergency situation
- •Patient with chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis)
- •Patient that needs a surgery for restoration of continuity
- •Patient pregnant, breastfeeding, or during periods of genital activity using no contraception.
- •Patient with contraindications to nefopam, morphine, or paracetamol
- •Patient with chronic obstructive pulmonary disease, renal or severe hepatic impairment
- •Patient under analgesics treatment
- •Patient who participated in a clinical study in the previous 6 months.
研究组 & 干预措施
control group
Placebo Comparator
干预措施: saline solution (Other)
Nefopam group
Experimental
干预措施: Nefopam (Drug)
结局指标
主要结局
Estimate morphine consumption
时间窗: over 48 hours
mg
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
A Comparison of Nefopam-propacetamol Combination and Propacetamol for Postoperative Quality of Recovery After Laparoscopic NephrectomyRenal TumorNCT01833728Yonsei University16
已完成
3 期
Nonopioid Analgesics and CholecystectomyCholecystectomyPain, PostoperativeOpioid UseNCT04622813American University of Beirut Medical Center90
已完成
4 期
Additional nefopam reduces postoperative pain after primary total knee arthroplasty: a randomized controlled trialTotal knee arthroplastyPainNefopamTotal knee arthroplastyPainNefopamTCTR20220814002Phyathai 3 Hospital80
尚未招募
Unknown
The analgesic effect of nefopam on postoperative pain and quality of recovery in patients undergoing laparoscopic cholecystectomy: A randomized, single-blind, prospective studyDiseases of the digestive systemKCT0008281The Catholic University of Korea, Eunpyeong St. Mary's Hospital40
已完成
不适用
Postoperative analgesic effect of nefopam monotherapy and nefopam-fentanyl polytherapy in patients underwent laparoscopic cholecystectomyKCT0004053Chosun University Hospital78