跳至主要内容
临床试验/NCT07052604
NCT07052604招募中不适用

Antibiotic Treatment for Pneumonia Caused by Stenotrophomonas Maltophilia in ICU Patients

Centre Hospitalier de Saint-Denis1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2023年12月15日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
300
试验地点
1
主要终点
patient survival based on the antibiotic treatment strategy used (monotherapy vs. combination therapy and 7 vs. 14 days duration).

研究概览

简要总结

This study looks at how different antibiotic treatments affect patients in intensive care who have pneumonia caused by the bacteria Stenotrophomonas maltophilia. It compares using one antibiotic versus two antibiotics, and treatment lengths of 7 days versus 14 days, to see which approach helps patients survive better. The study also examines how resistant the bacteria are to antibiotics and how often the pneumonia comes back.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients (age ≥ 18 years)
  • Hospitalized in Medical Intensive Care Unit between January 1, 2018, and December 31, 2023
  • Intubated and mechanically ventilated
  • Diagnosed with ventilator-associated pneumonia caused by Stenotrophomonas maltophilia

排除标准

  • Patients under 18 years old
  • Patients who refuse the use of their data for research purposes

结局指标

主要结局

patient survival based on the antibiotic treatment strategy used (monotherapy vs. combination therapy and 7 vs. 14 days duration).

时间窗: 28 days

次要结局

未报告次要终点

研究者

发起方
Centre Hospitalier de Saint-Denis
申办方类型
Other
责任方
Sponsor

研究点 (1)

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