Myasthenia Gravis and Psyche
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,399
- 试验地点
- 1
- 主要终点
- Questionnaire Survey (Patient)
研究概览
简要总结
The purpose of the study is to systematically capture and characterize mental comorbidities for patients with myasthenia gravis. Anxiety disorders and depression for example, can negatively affect the quality of life and lead to e.g. unemployment and early retirement especially in young patients.
Additionally the researchers want to find out in what way certain aspects of the disease have an influence on the quality of life, and whether different concepts of coping with the disease have different effects on the quality of life for patients with myasthenia gravis.
During the study, close relatives of patients will also be asked to provide input about their current stress situation in the context of supporting their relative.
Based on the results, the investigators want to improve and supplement established treatment concepts, to ensure a more comprehensive and individual treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Myasthenia Gravis
- •Age ≥18 years
排除标准
- 未提供
结局指标
主要结局
Questionnaire Survey (Patient)
时间窗: directly after inclusion in the study
* Questionnaire for self-completion by patients containing questions about general information, information on myasthenia, information on diagnosis of mental illness and psychotherapeutic care * Hospital Anxiety and Depression Scale (HADS - questionnaire for self-completion by patients to determine the levels of anxiety and depression) * Breslau scale PTBS-7 (questionnaire for self-completion by patients to determine the levels of Probability of posttraumatic stress disorder (PTSD)) * Mya Quality of Life 15 (Mya QoL15 - questionnaire for self-completion by patients for use as a measure of health outcome) * Freiburg questionnaire for coping (FKV - questionnaire is used to assess disease processing modes at the levels of cognition, emotion, and behavior)
次要结局
- "Häusliche Pflegeskala" (HPS)(directly after inclusion in the study)
研究者
Andreas Meisel
Prof. Dr. med.
Charite University, Berlin, Germany