Effectiveness of nebulization by high nasal flow during acute respiratory decompensations of chronic respiratory insufficiency.

CHU DE POITIERS0 个研究点目标入组 25 人开始时间: 2017年6月2日最近更新: 2021年5月25日

适应症

试验速览

暂无简介。

•All patients in the Poitiers University Hospital admitted for acute decompensation of chronic obstructive pulmonary disease (COPD, continuous dyspnea asthma) admitted to the medical resuscitation department and Continuing Care Units will be included in the study,
•They have the following inclusion criteria:
•- Age = 18 years
•- Respiratory decompensation with respiratory acidosis (pH> 7.25, FR <35, Glasgow 15),
•- Indication to a treatment with ß2-mimetic in nebulization,
•- Patient capable of answering simple questions despite dyspnea,
•- Information given to the patient and collection of consent.
•- Free subject, without guardianship or curatorship or subordination
•- Patients benefiting from a Social Security scheme or benefiting from it through a third party
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 22
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 3

•All patients will be excluded from the study if one of the following criteria
•- Age <18 years
•- Indication to an urgent intubation,
•- Contra-indication to ß2-mimetics,
•- Existence of non-respiratory organ failure (hemodynamic failure, neurological failure)
•- Patients with non-cardio-selective beta-blockers during the study,
•- Patients not benefiting from a Social Security scheme or not benefiting from it through a third party
•- Persons benefiting from enhanced protection, ie minors, pregnant women, nursing mothers, persons deprived of their liberty by a judicial or administrative decision, persons staying in a health or social institution, adults under legal protection, and Patients in emergencies.
•- Pregnant or nursing women, women of childbearing age who do not have effective contraception (hormonal / mechanical: oral, injectable, transcutaneous, implantable, intrauterine device, or surgical: tubal ligation, hysterectomy, total ovariectomy )

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