Neuropathic Pain and Traditional Medicine Syndromes in Herpes Zoster: a Cross-Sectional Study Conducted At Le Van Thinh Hospital, Vietnam
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Neuropathic Pain Severity in Herpes Zoster Patients
研究概览
简要总结
This study investigates the relationship between neuropathic pain characteristics and Traditional Chinese Medicine (TCM) syndromes in patients with Herpes Zoster (HZ). The study aims to integrate objective pain assessment tools, such as the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale, with TCM diagnostic classifications to enhance individualized treatment strategies. Conducted at Le Van Thinh Hospital, Vietnam, this cross-sectional study includes 80 HZ patients, assessing their pain levels and corresponding TCM syndromes. The findings will contribute to a more comprehensive approach to pain management in Herpes Zoster.
详细描述
This study is a cross-sectional and case series study conducted at Le Van Thinh Hospital, Ho Chi Minh City, Vietnam, between January and June 2024. It aims to evaluate the correlation between neuropathic pain characteristics and Traditional Chinese Medicine (TCM) syndromes in patients with Herpes Zoster (HZ). The study includes 80 participants diagnosed with HZ, whose pain severity is assessed using the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale. The participants are classified into TCM syndromes based on standard diagnostic criteria, including Liver Meridian Depression and Heat Syndrome (LMD), Spleen Deficiency and Dampness Retention Syndrome (SDA), and Qi Stagnation and Blood Stasis Syndrome (QSA).
The primary objectives of the study are:
To determine the prevalence of different TCM syndromes in HZ patients. To analyze the correlation between LANSS scores and specific TCM syndromes. To provide insights into the integration of objective neuropathic pain assessment tools with traditional diagnostic frameworks.
Data collection includes demographic characteristics, medical history, pain characteristics, TCM diagnostic features, and clinical examination results. Statistical analyses include correlation tests and multinomial logistic regression to assess the relationship between LANSS pain scores and TCM syndromes.
The study findings will contribute to a better understanding of the relationship between neuropathic pain and TCM syndromes in Herpes Zoster. The results may help refine diagnostic approaches and optimize integrative treatment strategies for pain management in patients with HZ.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged ≥18 years
- •Clinically diagnosed with Herpes Zoster (HZ) based on European Consensus Guidelines
- •Experiencing neuropathic pain associated with HZ
- •Willing to provide informed consent
排除标准
- •History of chronic pain conditions unrelated to HZ
- •Receiving immunosuppressive therapy or diagnosed with immunodeficiency disorders
- •Patients who had already received antiviral or analgesic treatment before evaluation
- •Patients unable or unwilling to provide informed consent
结局指标
主要结局
Neuropathic Pain Severity in Herpes Zoster Patients
时间窗: Baseline (Day 1)
Measured using the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale. LANSS scores will be used to determine the severity of neuropathic pain in study participants.
次要结局
- Correlation Between Neuropathic Pain and Traditional Medicine Syndromes(Baseline (Day 1).)
研究者
Do Thanh Sang
University of Medicine and Pharmacy at Ho Chi Minh City
University of Medicine and Pharmacy at Ho Chi Minh City