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临床试验/CTRI/2024/08/072206
CTRI/2024/08/072206尚未招募2/3 期

A Comparative Clinical Study To Evaluate the Efficacy of Irsal-E-Alaq (Leech Therapy) And Marham-E-Quba in the Management of Quba (Dermatophytosis)

State unani medical college and hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年8月15日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
1.Pruritus

研究概览

简要总结

Quba is also known as dermatophytosis, tinea or ringworm. It is one of the commonest and oldest skin disease. Dermatophytosis is a fungal infection that is characterized by the infection of keratinized tissue such as epidermis, hair and nails caused by a group of closely related filamentous fungi called dermatophytes. Dermatophytosis usually present with typical annular or arcuate or polycyclic lesion which spread centrifugally. margin is active showing papulovesicles, pustule and scaling but center is relatively clear. it is associated with itching, scaling, dryness sometimes fish like scaly lesion shed off from skin.

Dermatophytosis is a curable fungal disease. it is usually treated by antifungal topical agents and oral medications, but there are certain limitations that need to be addressed like costly medications, long term therapy, recurrence of the disease, drug resistant and severe side effects of antifungal drugs.

In unani system of medicine, many topicals and systemic drugs are being used to treat this disease. similarly most of the unani scholars have recommended various regimenal therapies, which are quite effective to treat quba. these therapies are Irsal-e-alaq (leech therapy), fasd (venesection), hijama-bil-shurt (wet cupping), zimaad (paste), marham (ointment), tila (liniment).

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Clinically Diagnosed patients of Quba on the basis of signs & symptoms and positive KOH examination.
  • Age group 18-60 years.
  • Patients of both genders.
  • Patients not taking any other drugs for Quba.
  • No apparent pathology of the skin.
  • Patients who are willing to sign informed consent.
  • Patient who would be agree to sign the informed consent and follow the protocol.

排除标准

  • Patients below the age of 18 years and above the age of 60 years.
  • Pregnant and lactating women.
  • Known case of bleeding disorder and anaemia.
  • Known case of acute infection and septicaemia.
  • Known cases of severe concomitant skin disease like- Psoriasis, Eczema, impetigo, erysipelas, pityriasis rosea etc.
  • Patient on immuno-compromised drugs.
  • Known cases of severe systemic & metabolic diseases like- Diabetes Mellitus, Hypertension, Hepatitis B, Hepatitis C, and HIV.
  • Non-compliance with the study protocol.
  • Obese patient.
  • Patients who do not want to give their consent for study.

结局指标

主要结局

1.Pruritus

时间窗: 0, 7, 14, 21, 28 Days

2.Erythema

时间窗: 0, 7, 14, 21, 28 Days

3.Size of lesion

时间窗: 0, 7, 14, 21, 28 Days

4.Number of lesion

时间窗: 0, 7, 14, 21, 28 Days

5.Scaling

时间窗: 0, 7, 14, 21, 28 Days

次要结局

  • 1.KOH mount(2.Dermatology)

研究者

发起方
State unani medical college and hospital
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Junaid Tahseen

State unani medical college and hospital, Himmatganj,Prayagraj, Uttar pradesh (211016)

研究点 (1)

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