ACTRN12621001117808招募中未知
Pre-treatment dihydropyrimidine dehydrogenase (DPYD) genotyping to individualise fluoropyrimidine-based chemotherapy: An evaluation of clinical implementation and treatment-related toxicity.
Queensland Health - Metro North Health0 个研究点目标入组 280 人开始时间: 2021年8月23日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 280
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •a.Pathologically confirmed malignancy for which treatment with a fluoropyrimidine at full dose (with or without other chemotherapy agents or radiation) is deemed clinically appropriate
- •b.Adult patient (> 18 years)
- •c.Receiving their first dose of fluoropyrimidine (either as a single agent or in combination) between 1 July, 2021 and 30 June, 2022.
- •d.Willing to provide blood sample for pharmacogenetic testing
排除标准
- •a.Inability to provide informed consent
- •b.Prior use of fluoropyrimidines
- •c.Women who are pregnant or breast-feeding
- •d.Patients with a previously known homozygous polymorphic genotype or compound heterozygous genotype for DPYD.
研究者
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