Oxytocinergic Modulation of Perceived Social Exclusion
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Neural activity changes associated with oxytocin administration
研究概览
简要总结
The aim of the present experiment is to examine oxytocin's behavioral and neural effects on social pain empathy
详细描述
In the current study, the investigators plan to examine whether oxytocin modulates behavior and neural activity during observing another person being excluded in an online ball-tossing game (a modified cyberball paradigm).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 30 Years(Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •healthy participants without past or current psychiatric or neurological disorders
排除标准
- •history of head injury
- •medical or psychiatric illness
- •smoking or drinking 24 hours before experiment
研究组 & 干预措施
placebo group
male participants with placebo treatment
干预措施: placebo treatment (Drug)
oxytocin group
male participants with oxytocin treatment
干预措施: oxytocin treatment (Drug)
结局指标
主要结局
Neural activity changes associated with oxytocin administration
时间窗: 45-60 minutes after drug administration
fMRI-assessed brain activity during observing other being socially excluded
次要结局
- Behavioral changes associated with oxytocin administration: ball-tossing(45-60 minutes after drug administration)
研究者
Keith Kendrick
Professor
University of Electronic Science and Technology of China
