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临床试验/NCT01624831
NCT01624831终止不适用

Social Cognition in Longstanding Psychosis

University of Arizona1 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2011年11月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
入组人数
9
试验地点
1
主要终点
Emotion Recognition

研究概览

简要总结

In the current study, the investigators propose to measure the five domains of social cognition identified by the National Institute of Mental Health (NIMH) as relevant to individuals with psychosis (i.e., theory of mind, attribution style, emotion recognition, social perception, and social knowledge). The investigators will also explore the association between different domains of social cognition and outcomes relevant to psychotic disorder (e.g., symptomatology, social functioning, and vocational functioning).

详细描述

There is growing evidence that individuals with longstanding psychotic disorders suffer from deficits in social cognition (i.e., the cognitive skills needed to successfully navigate social interactions). However, to date, there have been few attempts to measure multiple components of social cognition within the same population of individuals with psychosis. Thus, the interrelationships between various aspects of social cognition remain unclear. In the current study, the investigators propose to measure the five domains of social cognition identified by NIMH as relevant to individuals with psychosis (i.e., theory of mind, attribution style, emotion recognition, social perception, and social knowledge). The investigators will also explore the association between different domains of social cognition and outcomes relevant to psychotic disorder (e.g., symptomatology, social functioning, and vocational functioning).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of a schizophrenia spectrum disorder or an affective disorder with psychotic features per the Diagnostic and Statistical Manual of Mental Disorders-IV-Text Revised (DSM-IV-TR) criteria using the Structured Clinical Interview for the DSM-IV.
  • Duration of psychotic symptoms greater than or equal to 5 years determined using the Symptom Onset in Schizophrenia Inventory
  • Age 18-75
  • No evidence of mental retardation.
  • Able to provide informed consent as evidenced by passing the informed consent quiz with a score of 80% or greater.
  • Fluent in English as assessed per self-report from participant

排除标准

  • Unwilling or unable to complete study assessments (e.g., unable to read self-report questionnaires)
  • Subject is currently pregnant per subject's report

结局指标

主要结局

Emotion Recognition

时间窗: Baseline and 6 months

Change from baseline to 6 month assessment in ability to recognize emotions displayed by others assessed using the Facial Emotion Identification Test

Attribution Style

时间窗: Baseline and 6 months

Change from baseline to 6 month assessment in tendency to attribute events that occur to situational, personal, or internal factors assessed using the Internal, Personal, and Situational Attributions Questionnaire

Social Perception

时间窗: Baseline and 6 months

Change from baseline to 6 month assessment in ability to understand concrete and abstract components of everyday social interactions assessed using the Social Cues Recognition Test

Social Knowledge

时间窗: Baseline and 6 months

Change from baseline to 6 month assessment in knowledge of goals and actions associated with familiar and unfamiliar social activities assessed using the Situational Features Recognition Test

Theory of Mind

时间窗: Baseline and 6 months

Change from baseline to 6 month assessment in ability to identify the mental states of other individuals assessed using the Hinting Test

次要结局

  • Anxiety(Baseline and 6 months)
  • Depression(Baseline and 6 months)
  • Psychosis(Baseline and 6 months)
  • Social Functioning(Baseline and 6 months)
  • Service Utilization(Baseline and 6 months)
  • Self-Determination Needs Satisfaction(Baseline and 6 months)
  • Locus of Control(Baseline and 6 months)
  • Cognitive representation of illness(Baseline and 6 months)
  • Emotional Awareness(Baseline and 6 months)
  • Mindfulness(Baseline and 6 months)
  • Medication adherence(Baseline and 6 months)
  • Neuropsychological functioning(Baseline and 6 months)
  • Social Support(Baseline and 6 months)
  • Illness Uncertainty(Baseline and 6 months)
  • Relationship with familial caregivers(Baseline and 6 months)
  • Self-efficacy(Baseline and 6 months)
  • Experience of Stigma(Baseline and 6 months)
  • quality of life(Baseline and 6 months)
  • stage of recovery(Baseline and 6 months)
  • Coping skills(Baseline and 6 months)
  • Time perspective(Baseline and 6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nicholas Breitborde

Assistant Professor, Department of Psychiatry

University of Arizona

研究点 (1)

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