Incidence and clinical implication of new onset dysnatremia in critically ill patients to ICU in a tertiary care hospital in eastern area.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 450
- 试验地点
- 1
- 主要终点
- To investigate the impact of incidental sodium disorders on 28-day mortality of critically ill patients.
研究概览
简要总结
Phase 1: Observational
Collect baseline data on serum sodium at ICU admission and monitor daily sodium levels.
Classify sodium disorders as mild, moderate, or severe.
Phase 2: Interventional
Apply sodium management protocols tailored to each severity category.
Definitions of Sodium Disorders
Mild: Serum sodium levels between 125 to 150 mEq/L or a deviation of less than 10 mEq/L from the normal range.
Moderate: Serum sodium levels between 115 to 125 mEq/L or 150 to 160 mEq/L, or a deviation of 10 to 20 mEq/L from the normal range.
Severe: Serum sodium levels below 115 mEq/L or above 160 mEq/L, or a deviation of more than 20 mEq/L from the normal range.
Monitor outcomes such as mortality, ICU stay length
Primary Outcomes: Mortality rate and major complication rates.
Secondary Outcomes: Length of ICU stay, sodium level fluctuations
Until ICU discharge or death
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •All adult patients admitted to the ICU for conditions other than primary sodium disorders.
排除标准
- •Patients admitted to the ICU primarily due to a sodium disorder.
- •Patients receiving 3%sodium chloride for cerebro-protective strategy Patients under 18 years of age, pregnant women, and those with end-stage renal disease on chronic dialysis.
结局指标
主要结局
To investigate the impact of incidental sodium disorders on 28-day mortality of critically ill patients.
时间窗: till 28 days ICU stay or death or discharge
次要结局
- Determine the prevalence and progression of sodium disorders.(1. Length of ICU stay, fluctuations in sodium level)
研究者
Dr. Sagarika Panda
IMS AND SUM HOSPITAL, Bhubaneswar